Arimidex pills 1mg №28

Active ingredient and dosage form

Arimidex coated tablets
Anastrozole 1 mg;
28 pcs. packaged.

Mechanism of action

Arimidex has antitumor effect.

Indications and usage

Adjuvant therapy for early hormone-positive breast cancer in postmenopausal women; treatment of advanced breast cancer in postmenopausal women.

Dosage and administration

Inside Swallow arimidex pill whole with water; at the same time. Adults (including the elderly) - 1 mg 1 time per day (for a long time). If there are signs of disease progression, Arimidex should be discontinued.

Contraindications

hypersensitivity to anastrozole or other parts of Arimidex;
in premenopausal women;
severe renal failure (Cl creatinine less than 20 ml / min);
moderate or severe liver failure (safety and efficacy not established);
concomitant therapy with Tamoxifen;
pregnancy;
breastfeeding period;
children's age (safety and efficacy in children has not been established).

Adverse reactions

On the part of the vascular system: very often - "tides".
From the musculoskeletal system: often - arthralgia.
Reproductive system: often - vaginal dryness; rarely, vaginal bleeding (mainly during the first weeks after the cancellation or change of previous hormonal therapy with Arimidex).
On the part of the skin and skin appendages: often - thinning hair, skin rash; very rarely - polymorphic erythema (Stevens-Johnson syndrome).
On the part of the digestive system: often - nausea, diarrhea; rarely - anorexia, vomiting, increased activity of gamma-glutamine transferase and alkaline phosphatase.
From the nervous system: often - headache; rarely - drowsiness.

Special notes

Safety and efficacy in children has not been established.
In women with a receptor-negative tumor to estrogen, the efficacy of Arimidex has not been demonstrated, except in cases where there was a prior positive clinical response to tamoxifen.

Storage conditions

The drug should be stored in a dry, dark place at a temperature not higher than 25 ° C.