pharmachologic effect NSAIDs. It has anti-inflammatory and pronounced analgesic effect. The mechanism of action is due to inhibition of the enzyme cyclooxygenase and inhibition of the synthesis of prostaglandins. Ketanov has no sedative effect, does not affect opioid receptors. Ketanov does not cause depression of the respiratory center and does not affect the psychomotor functions. Indications and usageShort-term relief of pain of various origins, including: - postoperative pain (including after abdominal, gynecological, orthopedic operations); - pain syndrome with dislocations, fractures and injuries of soft tissues; - toothache (including after dental surgery); - pain in the postpartum period; - pain syndrome in oncological diseases; - pain syndrome in osteoarthritis; - sciatica. Ketanov are not indicated for use in chronic pain syndrome. OverdosageClinical data on acute overdose of the drug is not. AT experimental studies After a single injection of 100 mg / kg body weight, the animals showed symptoms such as decreased activity, diarrhea, difficulty breathing, and vomiting. Drug interactionsWith the simultaneous use of Ketanov with other NSAIDs increases the risk of side effects. In vitro ketorolac reduces the binding of Warfarin to plasma proteins. Storage conditionsThe drug should be stored in a dry, dark place at temperatures not above 25 ° C.
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