Ketanov pills 10mg №20

Indications and usage

 
Short-term relief of pain of various origins, including:
- postoperative pain (including after abdominal, gynecological, orthopedic operations);
- pain syndrome with dislocations, fractures and injuries of soft tissues;
- toothache (including after dental surgery);
- pain in the postpartum period;
- pain syndrome in oncological diseases;
- pain syndrome in osteoarthritis;
- sciatica.
Ketanov are not indicated for use in chronic pain syndrome.

Dosage and administration

For adults orally administered 10 mg every 4-6 hours. With severe pain, the dose can be increased to 20 mg 3-4 times a day. The injection solution is injected intramuscularly in a single dose of 10-30 mg (depending on the severity of pain), then 10-30 mg every 4-6 hours. The maximum duration of use of the solution for injection is 2 days.
The maximum daily dose of the drug (for any dosage form) is 90 mg.

For patients with a body weight of up to 50 kg, persons over 65 and patients with impaired renal function the maximum daily dose is 60 mg.

Adverse reactions

 
From the digestive system: stomatitis, nausea, constipation, dyspepsia, gastritis, erosive and ulcerative lesions of the gastrointestinal tract, dry mouth.
From the side of the central nervous system and peripheral nervous system: drowsiness, dizziness, nervousness, paresthesias.
From the urinary system: frequent urination, acute renal failure, nephrotic syndrome, interstitial nephritis.
Metabolism: increased levels of creatinine and / or urea in the blood plasma.
From the water and electrolyte balance: hypokalemia, hyponatremia.
Since the cardiovascular system: bradycardia, changes in blood pressure.
From the blood coagulation system: thrombocytopenia, purpura, hematoma formation, epistaxis, lengthening of clotting time.
On the part of the respiratory system: dyspnea.
Allergic reactions: hives.
Other: thirst.

Contraindications

 
- peptic ulcer of the stomach and duodenum in the acute phase;
- Gastrointestinal bleeding;
- bronchial asthma;
- severe cerebrovascular disorders;
- moderate and severe renal dysfunction, the risk of developing renal failure with hypovolemia and dehydration;
- violations of blood coagulation in history;
- hemorrhagic diathesis;
- simultaneous reception with other NSAIDs;
- pregnancy;
- childbirth;
- lactation (breastfeeding);
- children's and teenage age up to 16 years;
- Hypersensitivity to ketorolac and other NSAIDs.

Overdosage

 
Clinical data on acute overdose of the drug is not.
ATexperimental studies After a single injection of 100 mg / kg body weight, the animals showed symptoms such as decreased activity, diarrhea, difficulty breathing, and vomiting.

Drug interactions

 
With the simultaneous use of Ketanov with other NSAIDs increases the risk of side effects.
In vitro ketorolac reduces the binding of Warfarin to plasma proteins.

 
Store in a dry, dark place at a temperature not exceeding 25 ° C.