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Amelotex candles 7.5 mg №6
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Indications
Inflammatory and degenerative diseases of the joints (arthrosis, osteoarthritis), rheumatoid arthritis, ankylosing spondylitis (ankylosing spondylitis).
Dosage and administration
Inside of 7.5-15 mg 1 time / day.
Maximum Daily Dose makes 15 mg.
Adverse effects
Gastrointestinal: dyspepsia, nausea, vomiting, abdominal pain, constipation, intestinal colic, diarrhea, esophagitis, stomatitis; rarely - erosive and ulcerative lesions of the gastrointestinal tract.
From the side of the central nervous system: dizziness, headache, tinnitus.
Cardiovascular: increased blood pressure, palpitations, swelling, hot flashes.
Urogenital: changes in renal function laboratory values.
Hemic and lymphatic: anemia, leukopenia, thrombocytopenia.
Allergic reactions: bronchospasm, photosensitivity, pruritus, rash, urticaria.
Contraindications
Peptic ulcer and duodenal ulcer in the acute phase, pronounced abnormal liver function, renal failure (without hemodialysis), pregnancy, childhood and adolescence to 15 years, hypersensitivity to meloxicam and other NSAIDs (including salicylates).
Use during pregnancy and lactation
Contraindicated for use in pregnancy.
If necessary, use during lactation should decide on the termination of breastfeeding.
AT experimental studies no teratogenic effect of meloxicam was detected.
Application for violations of the liver
Contraindicated in marked disorders of the liver.
Application for violations of kidney function
Contraindicated in renal failure (without hemodialysis).
Use in children
Contraindicated in children and adolescents up to 15 years.
Special notes
With caution used in patients with gastrointestinal tract history.
Drug interaction
With simultaneous use may reduce the effectiveness of antihypertensive drugs (beta-blockers, ACE inhibitors, vasodilators).
With simultaneous use with anticoagulants increases the risk of bleeding.
With simultaneous use with diuretics increases the risk of renal failure in patients in a state of dehydration.
With simultaneous use with NSAIDs increases the risk of ulceration of the gastrointestinal tract and Gastrointestinal bleeding.
With simultaneous use with lithium preparations increases the concentration of lithium in the blood plasma.
With simultaneous use of Kolestiramin accelerates the elimination of meloxicam.
With simultaneous use with Methotrexate may increase myelodepressive action; with cyclosporine - may increase the nephrotoxic effect of cyclosporine.