Orthanol Capsules 20mg n28

Dosage form

Capsules

Composition

1 capsule contains Omeprazole 20 mg;
Excipients: gelatin, mareon, purified water.

Packaging

28 pcs.

Mechanism of action

Orthanol is an anti-ulcer agent, an inhibitor of H + -K + -ATP-ase. Hinders the activity of H + -K + -ATP-ases in the parietal cells of the stomach and thereby blocks the final stage of the secretion of hydrochloric acid. This leads to a decrease in basal and stimulated secretion, regardless of the nature of the stimulus. Due to a decrease in acid secretion, it reduces or normalizes the effect of acid on the esophagus in patients with reflux esophagitis.

Omeprazole has a bactericidal effect on Helicobacter pylori. Eradication of H. pylori with simultaneous use of omeprazole and antibiotics allows you to quickly arrest the symptoms of the disease, achieve a high degree of healing of the damaged mucous and persistent long-term remission and reduce the likelihood of bleeding from the gastrointestinal tract.

Indications and usage

Peptic ulcer and duodenal ulcer in the acute phase (including associated with Helicobacter pylori), reflux esophagitis, Zollinger-Ellison syndrome, erosive-ulcerative lesions of the stomach and duodenum, associated with the intake of NSAIDs.

Contraindications

Chronic liver diseases (includingin history), hypersensitivity to omeprazole, children up to 12 years.

Pregnancy and Breastfeeding

Due to the lack of clinical experience, omeprazole is not recommended for use during pregnancy. If necessary, use during lactation should decide on the termination of breastfeeding.

Dosage and administration

For ingestion a single dose is 20-40 mg. Daily dose - 20-80 mg; frequency of use - 1-2 times a day. The duration of treatment is 2-8 weeks.

Adverse reactions

Gastrointestinal: rarely - nausea, diarrhea, constipation, abdominal pain, flatulence.

From the side of the central nervous system: rarely - headache, dizziness, weakness.

Hemic and lymphatic: in some cases - anemia, eosinopenia, neutropenia, thrombocytopenia.

Urogenital: in some cases - hematuria, proteinuria.

Musculoskeletal system: in some cases - arthralgia, muscle weakness, myalgia.

Allergic reactions: rarely a skin rash.

Special notes

Before starting therapy, it is necessary to exclude the possibility of the presence of a malignant process (especially in case of a stomach ulcer), since Omeprazole treatment may mask the symptoms and delay the proper diagnosis.

Against the background of the use of omeprazole may be a distortion of the results of laboratory studies of liver function and indicators of the concentration of gastrin in the blood plasma.