Cerucal ampoules 10mg 2ml №10

Active ingredient

Cerucal pills white, round, flat, with a risk on one side, with a smooth surface and one-piece beveled edges.
1 pill contains Metoclopramide hydrochloride monohydrate 10.54 mg
(which corresponds to 10 mg of metoclopramide hydrochloride);
Excipients: potato starch, lactose monohydrate, gelatin, Magnesium stearate, precipitated silica;
in the package 50 pcs.

injection transparent colorless.
1 vial (2 ml) contains metoclopramide hydrochloride 10 mg;
Excipients: sodium sulfite, disodium EDTA, sodium chloride, water for injection;
in ampoules of 2 ml; in packaging of blister 5 ampoules; in box 2 packs.

Reglan - antiemetic drug. A specific dopamine receptor blocker, weakens the sensitivity of the visceral nerves, which transmit impulses from the pyloric region of the stomach and duodenum to the emetic center. Through the hypothalamus and the parasympathetic nervous system has a regulating and coordinating effect on the tone and motor activity of the upper part of the gastrointestinal tract (including the tone of the lower digestive sphincter alone).
Increases muscle tone of the stomach and intestines, accelerates gastric emptying, reduces hyperacid stasis, prevents pyloric and esophageal reflux. Stimulates intestinal motility.

Indications and usage

- vomiting and nausea of ​​various origins;
- Atonia and hypotonia of the stomach and intestines (including postoperative);
- biliary dyskinesia;
- reflux esophagitis;
- functional pyloric stenosis;
- to enhance peristalsis when conducting radiopaque studies of the gastrointestinal tract;
- paresis of the stomach with diabetes;
- as a means of facilitating duodenal intubation (to accelerate gastric emptying and the movement of food through the small intestine).

Contraindications

- pheochromocytoma;
- intestinal obstruction;
- bleeding from the gastrointestinal tract;
- perforation of the digestive tract;
- prolactin-dependent tumor;
- epilepsy;
- extrapyramidal movement disorders;
- I trimester of pregnancy;
- lactation (breastfeeding);
- children's age up to 2 years;
- hypersensitivity to metoclopramide;
- hypersensitivity to sodium sulfite, especially in patients with bronchial asthma and other allergic diseases (for the injection form of Cerukal).
Carefully It should appoint a drug for hypertension, bronchial asthma, abnormal liver function, hypersensitivity to procaine and procainamide, children aged 2 to 14 years.

Dosage and administration

Set individually depending on the clinical symptoms and the patient's age.
Adults and teenagers aged 14 and over administered orally at 10 mg 3-4 times / day.
If necessary, Cerucal can be administered intramuscularly or intravenously in a dose of 10 mg. The frequency of administration is 3-4 times / day.
The average duration of treatment is 4-6 weeks; in some cases - up to 6 months.
For children aged 2-14 years the maximum single dose for oral administration and for parenteral use is 0.1 mg / kg body weight; the maximum daily dose is 0.5 mg / kg.
Inside the drug should be taken 30 minutes before a meal.
Patients with impaired renal function correction of dosing regimen required.
With creatinine clearance of 60-11 ml / min, the dose is 15 mg / day, divided into 2 doses (10 mg and 5 mg).
Under Clearance