Venter pills 1000mg №50

the form:

pills

Composition

1 pill contains:
Active ingredient: sucralfate 1 g
Excipients: corn starch, talc, colloidal silicon dioxide, anhydrous, Magnesium stearate.

White oval pills with a notch on both sides.

Pharmacological properties

Interacting with proteins of necrotic tissue, ulcers or erosion, the drug forms a protective layer that for a long period of time protects the affected areas of the mucous membrane from the influence of aggressive factors (hydrochloric acid, pepsin and bile acids).
Moderately (30%) inhibits pepsin activity.
Reduces the absorption of phosphates from the gastrointestinal tract.
Sucralfate is poorly absorbed (5% disaccharide component and less than 0.005% aluminum Al3 +) in the gastrointestinal tract and therefore does not have a significant systemic effect. A small amount of the drug (3-5%)

:

Severe renal dysfunction, children under 4 years of age, hypersensitivity to sucralfate and other components of the drug. With care: chronic renal failure (CRF) (the risk of aluminum intoxication), pregnancy, lactation.

and period lactation

The safety of the drug during lactation has not been established.Use during pregnancy is possible if the benefit to the mother outweighs the potential risk to the fetus.

of application and doses

Inside, without chewing, washing down with a small amount of water, 1 hour before meals and before bedtime.
Peptic ulcer and duodenal ulcer in the acute phase:
by mouth 1 pill (1 g) four times a day or 2 pills (2 g) twice a day.
The maximum daily dose is 8 g. The average duration of the course of treatment is 4-6 weeks, if necessary up to 12 weeks.
Prevention of acute exacerbations of duodenal ulcer: 1 pill twice a day.
Reflux esophagitis: 1 pill three times a day before each meal and 1 pill at bedtime.
Hyperphosphatemia: 1 pill four times a day before meals and before bedtime.
In patients with hyperphosphatemia, with a decrease in plasma phosphate concentration, the dose of sucralfate may be reduced.
The duration of therapy for reflux of esophagitis, hyperphosphatemia, as well as for the prevention of exacerbations of gastric ulcer and duodenal ulcer is determined by the patient's clinical condition and the results of the examination in the dynamics, individually by the attending physician.
Children over 4 years old: 1/2 to 1 pill (0.5-1.0 g) four times a day one hour before meals and at night, i.e. at a dose of 40-80 mg per kg of body weight per day, divided into 4 doses.

act

Constipation, rarely - nausea, vomiting, diarrhea, flatulence, dry mouth, headache, insomnia, drowsiness, dizziness, gastralgia, pain in the lumbar region, allergic reactions (pruritus, rash, rash).

Overdosage

The risk of overdose is unlikely.
Symptoms: nausea, vomiting and epigastric pain.
Treatment: symptomatic.
With long-term intake of large doses, in the case of kidney failure, aluminum intoxication may develop, up to the development of encephalopathy (dysarthria, apraxia, myoclonus, dementia, convulsions, and in severe cases coma and death) and osteomalacia (pain, pathological fractures and deformities of the bones).
Treatment: discontinuation of Venter, hemodialysis, hemofiltration and peritoneal dialysis and deferoxamine.

Interactions with by others medicinal by means

If necessary, the simultaneous appointment of Venter and antacids, the latter should be taken 30 minutes before or 30 minutes after taking Venter.
Reduces the absorption of tetracyclines, cimetidine, Ranitidine, Ciprofloxacin, norfloxacin, Ofloxacin, Digoxin, indirect anticoagulants and theophylline (the interval between their intake should be at least 2 hours).
Reduces the absorption and equilibrium concentration of phenytoin (possibly renewed seizures). The interval between doses is 2 hours.

directions

With a lack of kidney function, it is necessary to control the concentration of aluminum and phosphate in the serum. The risk of aluminum accumulation in the body increases with the simultaneous use of preparations containing aluminum (some antacids). The introduction of Venter through a nasogastric tube can lead to the formation of Bezoar (calculus, which is formed in the digestive tract and is in the form of a ball) with other drugs or solutions for enteral feeding (it can bind protein).

Influence on the ability to drive and other mechanical means: there were no reports of a significant impact on the ability to drive a car and other mechanisms.

release

pills of 1 g. On 10 pills in the blister. 5 blisters of 10 pills along with instructions for use in a carton box.

storage

Store in a dry place at a temperature not exceeding 25 ° C.
Keep out of the reach of children.

shelf life

3 years.
Do not use after the expiration date.

Conditions holidays of pharmacies

On prescription.