Memantine pills 10mg №90

Pharmacology

Memantine Canon is a centrally acting muscle relaxant. Being a non-competitive antagonist of N-methyl-D-aspartate (NMDA) receptors, it has a modulating effect on the glutamatergic system. It regulates ion transport, blocks Calcium channels, normalizes membrane potential, improves the transmission of nerve impulses, improves cognitive processes, memory and learning ability, increases daily activity.

Indications

• Dementia of Alzheimer's type, vascular dementia, mixed dementia of all degrees of severity.
• Decreased memory, ability to concentrate and ability to learn.
• Cerebral and spinal spastic syndrome, including as a result of traumatic brain injury, multiple sclerosis, stroke.

Contraindications

Individual hypersensitivity to the drug, pronounced renal dysfunction, pregnancy, breastfeeding.

Carefullyprescribed to patients with thyrotoxicosis, epilepsy.

Dosage and administration

Memantine canon taken by mouth, while eating. The dosage regimen is set individually. It is recommended to begin treatment with the appointment of the minimum effective doses.

Adults with dementia during the 1st week of therapy - at a dose of 5 mg / day, 2nd week - at a dose of 10 mg / day, 3rd week - at a dose of 15–20 mg / day.If necessary, a further weekly dose increase of 10 mg is possible until a daily dose of 30 mg is reached.

The optimal dose is achieved gradually, with an increase in dose every week.

Adverse effects

Dizziness, fatigue, anxiety, irritability, nausea, feeling of "heaviness" in the head.

Special notes

The optimal dose is achieved gradually, with an increase in dose every week.

Drug interactions

With simultaneous use with barbiturates, neuroleptics, anticholinergic agents, the effects of the latter can be enhanced. When used together, it can change (increase or decrease) the effect of dantrolene or Baclofen, so the doses of drugs should be selected individually.

Overdosage

Symptoms: increased severity of side effects.

Treatment: gastric lavage, reception of Activated carbon, symptomatic therapy.

Storage conditions

At a temperature not higher than 25 ° С in places inaccessible for children.