Gastal pills №60

- against heartburn,

- pain,

- heaviness in the stomach

Dosage form

Lozenges

1 pill contains: active substances: aluminum hydroxide-magnesium carbonate gel 450.0 mg, Magnesium hydroxide 300.0 mg; excipients: mannitol (E421) 120.00 mg, sorbitol (E420) 50.00 mg, lactose monohydrate 30.00 mg, corn starch 75.80 mg, sodium cyclamate 7.00 mg, sodium saccharinate 0.20 mg, talc 28.00 mg, magnesium stearate 6.00 mg, peppermint flavoring 3.00 mg.

Antacid

Pharmacology

The drug Gastal is a combined antacid, which reduces the increased acidity of gastric juice and does not have a stimulating effect on the secretion of gastric juice. Aluminum hydroxide-magnesium carbonate gel and magnesium hydroxide provide immediate (immediately after ingestion) and prolonged (about 2 hours) neutralization of the hydrochloric acid of the gastric juice, while maintaining the acidity in the stomach at the physiological level (pH 3-5). One pill of the drug Gastal neutralizes 21.5 mmol of hydrochloric acid.

The drug Gastal suppresses the action of pepsin, lysolecithin and bile acids, eliminates dyspeptic symptoms. Strengthens protective and regenerative processes in the mucous membrane of the stomach.Aluminum ions have a cytoprotective effect due to increased secretion of mucin and sodium bicarbonate, activation of prostaglandin E2 and NO, the accumulation of epidermal growth factor at the site of damage to the mucous membrane, increasing the concentration of phospholipids in the walls of the stomach.

The drug Gastal does not have a systemic effect in patients with normal renal function. After interacting with the hydrochloric acid of gastric aluminum juice, the hydroxide reacts with phosphates and carbonates in the alkaline medium of the intestine and is excreted in the form of insoluble salts.

Magic hydroxide reacts with hydrochloric acid in the gastric juice to form magnesium chloride, which has osmotic properties and a mild laxative effect that neutralizes the fixative action of aluminum hydroxide in the small intestine. Magnesium ions are excreted in the form of insoluble carbonate.

Indications and usage

- Dyspeptic symptoms, such as discomfort or pain in the epigastrium, heartburn, acid regurgitation after errors in the diet, excessive use of ethanol, coffee, nicotine, etc.;

- Dyspeptic symptoms, such as discomfort or pain in the epigastrium, heartburn, acid regurgitation (and their prevention), resulting from the use of certain drugs (nonsteroidal anti-inflammatory drugs, glucocorticosteroids, etc.);

- A condition accompanied by increased acid formation: peptic ulcer, gastritis, reflux esophagitis; hernia of the esophageal opening of the diaphragm.

Contraindications

Hypersensitivity to salts of aluminum, magnesium or other components of the drug; severe renal failure; Alzheimer's disease; hypophosphatemia; lactose intolerance, lactose deficiency or glucose-galactose malabsorption; children's age up to 6 years.

Inside, gradually dissolving in the mouth.

Adults and children over 12 years old with a body weight of at least 50 kg

1-2 pills 4-6 times a day approximately 1 hour after meals and at bedtime, but not more than 8 pills per day. The duration of treatment is not more than 2 weeks.

Adults and children over 12 years old weighing less than 50 kg, children aged 6 to 12 years

The dose is half the recommended dose for adults and children over 12 years old with a body weight of at least 50 kg. The duration of treatment is not more than 2 weeks.

Overdosage

Symptoms of acute overdose are not described.

Adverse reactions

Nausea, constipation, diarrhea, change in taste. In exceptional cases, allergic reactions are possible.

Storage conditions

Store at a temperature not higher than 25^aboutC. Keep out of the reach of children.