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Kvamatel lyophilisate + solvent for intravenous injection 20mg №5
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/Quamatel
Active ingredient and dosage form
Kvamatel - coated tablets: 1 pill contains Famotidine 20 and 40 mg, excipients in the core of the tablet: colloidal silica, anhydrous; Magnesium stearate; Povidone K 90; sodium carboxymethyl starch, type A; talc; corn starch; lactose monohydrate;
in blister pack of 14; in a carton of cardboard 2 blisters (tab. 20 mg) or in a blister 14 pcs.; in a cardboard box 1 blister (tab. 40 mg).
Kvamatel - lyophilized powder for solution for injection:
1 fl. contains famotidine 20 mg, excipients: aspartic acid; mannitol; solvent: sodium chloride; water for injections;
in vials complete with the solvent in ampoules, ampoule knife; in the box 5 sets.
Mechanism of action
Kvamatel has an anti-ulcer effect.
Indications and usage
For oral administration:
peptic ulcer of the duodenum and stomach in the acute phase, prevention of relapse;
treatment and prevention of symptomatic gastric and duodenal ulcers (associated with the use of NSAIDs, stress, postoperative);
erosive gastroduodenitis;
functional dyspepsia associated with increased gastric secretion;
reflux esophagitis;
Zollinger-Ellison syndrome;
prevention of recurrence of bleeding from the upper GI tract;
prevention of gastric juice aspiration during general anesthesia (Mendelssohn's syndrome).
For on / in the introduction:
peptic ulcer of the duodenum and stomach in the acute phase;
symptomatic ulcers and their prevention;
reflux esophagitis;
Zollinger-Ellison syndrome;
prevention of gastric juice aspiration during general anesthesia (Mendelssohn’s syndrome);
bleeding from the upper GI tract (as part of a comprehensive treatment).
Contraindications
Hypersensitivity to famotidine and other histamine H2 receptor blockers;
pregnancy;
lactation;
childhood.
Adverse reactions
Dry mouth, nausea, vomiting, flatulence, constipation, diarrhea, anorexia, increased liver enzymes, headache, dizziness, tinnitus, fatigue, drowsiness, transient mental disturbances, fever, arrhythmia, muscle pain, pain in the joints, alopecia, common acne, dry skin, itching, bronchospasm, other manifestations of hypersensitization. Very rarely - agranulocytosis, pancytopenia, leukopenia, thrombocytopenia.
Dosage and administration
Kvamatel take inside.In case of gastric ulcer and duodenal ulcer in the acute stage: 40 mg 1 time per day, at bedtime or 20 mg 2 times per day. If necessary, the daily dose of quamel can be increased to 80-160 mg. The course of treatment is 4-8 weeks. In order to prevent relapse: 20 mg 1 time per day before bedtime. When reflux esophagitis: 20-40 mg 2 times a day for 6-12 weeks. With Zollinger-Ellison syndrome: the dose of the drug and the duration of the course of treatment are set individually, the initial dose is usually 20 mg every 6 hours. With general anesthesia to prevent aspiration of gastric juice: 40 mg in the evening before the operation and / or in the morning before the operation.
Kvamatel administered in / in, jet or drip (used when it is impossible ingestion). The usual dose is 20 mg 2 times a day (every 12 hours).
Zollinger-Ellison syndrome: the initial dose is 20 mg every 6 hours. Subsequently, the dose depends on the level of secretion of hydrochloric acid and the clinical condition of the patient.
For the prevention of acid complications with a possible aspiration injected into / in 20 mg of the drug on the eve of the operation or at least 2 hours before the operation.
A single dose with a / in the introduction should not exceed 20 mg. The daily dose of Kvamatel with the on / in the introduction of 20 mg every 12 hours.
Storage conditions
In the dark place at a temperature of 25 ° C. Shelf life -5 years.