Mirror 10mg/ml solution 30ml

ZERKALIN RR 10MG / ML FL. 30 ML

Description

Group

Lincomycin group antibiotics

Composition

Active ingredient: Clindamycin hydrochloride.

International non-proprietary name

Clindamycin

Synonyms

Dalatsin, Dalacin T, Dalacin C, Dalacin C phosphate, Klimitsin, Klimitsin T, Clindamycin, Clindafer, Clindacin, Clindovit

pharmachologic effect

The antibiotic of the group of lincosamides, is active against all strains of Propionibacterium acnes. After application to the skin, the amount of free fatty acids on the skin surface decreases from approximately 14% to 2%. It quickly accumulates in comedones, where it shows antibacterial activity. The average concentration of the antibiotic in the contents of comedones after the application of the solution significantly exceeds the minimum inhibitory concentration for all strains of Propionibacterium acnes, the causative agent of acne. After applying the solution in the blood plasma and urine to the skin, very low concentrations of the active substance are determined.

Indications for use

Used to treat acne (acne vulgaris).

Contraindications

Hypersensitivity to the active substance or Lincomycin, as well as other components of the drug in history; Crohn's disease, ulcerative and pseudomembranous colitis (including a history).

Side effect

Usually well tolerated, however, when the local application of the solution may irritation (at the site of application), burning, itching, dry skin, erythema, peeling, increased sebum, contact dermatitis.With resorption, there is a likelihood of pseudomembranous enterocalitis.

Interaction

Simultaneous use with other drugs for the treatment of acne, containing exfoliating, emollient and abrasive substances (for example, benzoyl peroxide, tretinoin, resocinol, salicylic acid, sulfur) is not recommended because of the possible cumulative irritant effect on the skin. There is cross-resistance between the active substance and lincomycin. May enhance the action of muscle relaxants, disrupting neuromuscular transmission.

Dosing and Administration

Apply to the affected areas of clean, dry skin twice a day, morning and evening. Treatment is carried out before the development of an adequate response in the absence of side effects.

Overdose

Unlikely because of the peculiarities of the local drug.

special instructions

It should be taken with caution when prone to allergic reactions. Avoid contact with the mucous membrane of the eyes and mouth. In case of contact with sensitive surfaces (eyes, skin abrasions, mucous membranes), this area should be washed with plenty of cool water. With the development of diarrhea, the drug should be discontinued and, if necessary, carry out appropriate diagnostic and therapeutic measures.

Storage conditions

Store in a dry, protected from light, out of reach of children at a temperature not higher than 25 C.

Vacation order

Over-the-counter