Buy Tamoxifen tablets 10mg №30
  • Buy Tamoxifen tablets 10mg №30

Tamoxifen pills 10mg №30


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Active ingredient and dosage form

1 pill contains Tamoxifen citrate 10, 20, or 30 mg;
10, 30 or 50 pills per pack.

Mechanism of action

Antitumor, antiestrogenic.
Tamoxifen It is a nonsteroidal anti-estrogen agent, which also has poor estrogenic properties. Its action is based on the ability to block estrogen receptors. Tamoxifen, and also some of its metabolites compete with estradiol at the site of binding to the cytoplasmic estrogen receptors in the tissues of the mammary gland, the wedge, the womb, the anterior pituitary gland in tumors with a high content of estrogen receptors. In contrast to the estrogen receptor complex, the receptor complex of tamoxifene does not stimulate DNA synthesis in the nucleus, but inhibits cell division, which leads to regression of tumor cells as a result of their death.

Estrogen-dependent breast cancer in women (especially in menopause) and in men.

The drug can be used for the treatment of ovarian cancer, endometrial cancer, kidney cancer, melanoma, soft tissue tissue in the presence of estrogen receptors in the tumor, and also for the treatment of prostate cancer with other lectures.


Pregnancy, thrombophlebitis.
Restrictions on the use of: leukopenia, thrombocytopenia, hypercalcemia.

Dosage and administration

The dosage regimen is usually set individually depending on the situation. The daily dose is 20-40 mg.

As a standard dose, it is recommended to take 20 mg of tamoxifene orally daily for a long time until signs of disease progression appear.

Tablets should be taken unzipped, zapivaya by a small amount of liquid, with food in a single dose in the morning, or by dividing the required dose into two in the morning and evening.

Adverse reactions

Nausea, vomiting, redness and dry skin, dizziness, headache, drowsiness, depression, pain in the bones and lesions, itching in the genital area, vaginal bleeding, swelling, alopecia, visual disturbances, thromboembolism, phlebitis. In very rare cases - changes in the blood picture, an increase in the ovaries, disturbances (up to termination) of the menstrual cycle.

Before treatment, patients must undergo gynecological (to exclude pregnancy) and therapeutic examination; women of childbearing age need to use reliable contraceptives (not oral), and contraception must continue for 3 months after the end of the course.
When treatment should periodically monitor the Calcium in the blood, the blood picture (leukocytes, platelets). Special care and careful observation are necessary in patients with pathology of the kidneys, diabetes mellitus,ophthalmologic diseases and thromboembolic disorders (even in history).

It is not very effective in treating patients with metastases (especially in the liver).

Drug interactions

With the simultaneous appointment of tamoksifena and cytostatics increases the risk of thrombosis.
There are reports of the potentiation of the anticoagulant effect of the coumarin series by drugs (eg, parpharin).
Medicines that reduce the renal excretion of calcium, such as diuretics of the thiazide series, may increase the risk of hypercalcemia.
The simultaneous use of tamoxifen with other hormonal preparations (especially estrogen-containing counter-receptacles) leads to the weakening of the specific action of both drugs.

Storage conditions

B. List: In a dry, the dark place at a temperature below 25 ° C.
Shelf life - 2 years