Lopedium capsules 2mg №10

Dosage form

capsules

Composition

1 capsule contains: Loperamide hydrochloride 2 mg.

Excipients: lactose monohydrate, corn starch, talc, Magnesium stearate.

Packing

In the blister 10 capsules. In packing 1 blister.

Mechanism of action

Lopedium capsules - symptomatic antidiarrheal drug.

By binding to the opioid receptors of the intestinal wall, loperamide reduces the tone and motility of the smooth muscles of the intestine. Slows peristalsis and increases the time of passage of intestinal contents. Increases the tone of the anal sphincter. Contributes to the retention of feces and the reduction of the urge to defecate.

The action comes quickly and lasts 4-6 hours.

Indications and usage

- Symptomatic treatment of acute and chronic diarrhea of ​​allergic, emotional, medicinal and radiation genesis.
- Diarrhea with a change in diet, the qualitative composition of the food, violation of absorption and metabolism.
- As an adjuvant for infectious diarrhea.
- Regulation of stools in patients with ileostomy.

Contraindications

- Diverticulosis.
- intestinal obstruction.
- Ulcerative colitis in the acute stage.
- Diarrhea on the background of acute pseudomembranous enterocolitis.
- Monotherapy for dysentery and other gastrointestinal infections.
- I trimester of pregnancy.
- Lactation period.
- Children's age up to 6 years.
- Hypersensitivity to the drug.

The drug should be used with caution in patients with liver failure.

Dosage and administration

The drug should be taken orally, swallow capsules, without chewing, with 100 ml of water.

In acute and chronic diarrhea:
Adults are prescribed initially at 4 mg, then 2 mg after each bowel movement in the case of liquid stool. The maximum daily dose is 16 mg.
Children over 6 years old are prescribed 2 mg after each bowel movement in the case of loose stools. The maximum daily dose is 6 mg.

After stool normalization or in the absence of stool for more than 12 hours, treatment should be discontinued.

Special notes

In the absence of effect after 2 days of Lopedium application, it is necessary to clarify the diagnosis and exclude infectious genesis of diarrhea.

If the treatment develops constipation or bloating, the drug should be discontinued.

During treatment, it is necessary to compensate for the loss of fluid and electrolytes.

Each Lopedium capsule corresponds to 0.01 XE.

In patients with impaired liver function, careful monitoring of signs of toxic CNS damage is necessary. The drug should be used with caution in patients with liver failure.

Influence on ability to drive motor transport and control mechanisms: in case of drowsiness or dizziness, you should refrain from driving and working with machinery.

Overdosage

Symptoms: stupor, incoordination, drowsiness, miosis, muscular hypertonia, respiratory depression, intestinal obstruction.
Treatment: symptomatic - Activated carbon, gastric lavage, mechanical ventilation. Medical observation of the patient for at least 48 hours is required. Antidote naloxone. Since loperamide has a longer duration of action than naloxone, it is possible to reintroduce the latter.

The drug should be stored at a temperature not higher than 25 ° C.