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Enterol powder 250mg sachet №20
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Composition
1 bag of powder for the preparation of oral suspension contains:
Active ingredients
Saccharomyces boulardii lyophilisate
Excipients
Lactose monohydrate 13 mg, fructose 188.76 mg, colloidal silicon dioxide 2.50 mg, tutti-frutti flavoring 1.74 mg.
In 1 bag of 306 mg of powder for preparation of oral suspension. In a carton box 20 bags.
Indications for use
- Treatment and prevention of diarrhea of various etiologies in adults and children from 1 year with:
- Dysbacteriosis.
- Irritable bowel syndrome.
- Enterocolitis.
- Antibiotic-associated diarrhea.
- Travelers' diarrhea.
- Diarrhea caused by Clostridium difficile.
Clinical Pharmacology
Saccharomyces boulardii is a probiotic.
According to the WHO definition, these are live microorganisms, applied in adequate quantities, which have a healing effect on the human body.
Saccharomyces boulardii has an antimicrobial effect, due to the antagonistic effect against pathogenic and conditionally pathogenic microorganisms:
- Clostridium difficile.
- Candida albicans.
- Candida kruesei.
- Candida pseudotropicalis.
- Klebsiella pneumoniae.
- Pseudomonas aeruginosa.
- Salmonella typhimurium.
- Yersinia enterocolitica.
- Escherichia coli.
- Shigella dysenteriae.
- Staphylococcus aureus.
- Entamoeba histolitica and Lambliae.
Saccharomyces boulardii has an anti-toxin action against bacterial cyto- and enterotoxins, increases the enzymatic function of the intestine.
The cell wall component of Saccharomyces boulardii mannitol is a substrate for the pathogenic strains of Escherichia coli and Salmonella typhimurium, which causes their adhesion (attachment) to the surface of Saccharomyces boulardii and subsequent excretion from the body.
Saccharomyces boulardii is naturally resistant to antibiotics.
Saccharomyces boulardii is not eubiotic, that is, it is not part of the microflora of a healthy human body, respectively, after taking the drug Saccharomyces boulardii passes through the digestive tract unchanged without colonization and is completely eliminated from the body within 2 to 5 days after stopping the administration.
Use during pregnancy and lactation
Enterol use during pregnancy or lactation is justified if the expected benefit outweighs the potential risk.
Contraindications
- Hypersensitivity to any of the components of the drug.
- The presence of a central venous catheter (as described rare cases of fungemia in patients with a central venous catheter after mechanical ingestion of the drug into the systemic circulation through the catheter as a result of the actions of medical personnel in hospital conditions).
Side effect
In rare cases, individual sensitivity to the components of the drug may occur.
Interaction
Enterol is not taken in conjunction with antifungal drugs.
Compatible with antibiotics.
Overdose
Data on overdose of the drug is not currently available.
Dosage and administration
On 2 - 8 bags a day in 1 hour prior to food. The contents of the bag mixed with water or another drink.
- Children from 1 year to 3 years: 1 - 3 sachets 2 times a day.
- Children from 3 years and adults: 2 - 4 sachets 2 times a day.
For the treatment of acute diarrhea of viral, bacterial or protozoal etiology, the course of treatment is 5 to 10 days.
For the prevention of antibiotic-associated diarrhea, a day-to-day course of treatment is consistent with the course of antibiotic use.
For the prevention of recurrence of infection caused by Clostridium difficile, in combination with Metronidazole or Vancomycin, the treatment is 1 month.
For the prevention of travelers' diarrhea, the daily treatment course corresponds to the duration of the trip.
For the treatment of irritable bowel syndrome, the use of the drug should be continued until the symptoms disappear.
The drug for the treatment of acute diarrhea must necessarily be accompanied by rehydration (heavy drinking).
Precautionary measures
Do not drink hot and alcoholic beverages.
Do not heat the product mixed in water or other beverage in a microwave oven (microwave oven). Water or drink, if necessary, is heated in a microwave oven, and then add the drug in warm water.
If after two days of use of the drug Enterol for the treatment of acute diarrhea does not improve, as well as with a rise in temperature, detection of blood or mucus in the stool, you should immediately contact your doctor.
A feeling of thirst and dry mouth indicates insufficient rehydration.
The actions of the doctor (paramedic) or the patient when they skip taking one or more doses of the drug: not required.
Impact on the ability to drive vehicles and mechanisms
No adverse effect of the use of the drug Enterol on the ability to drive and complex mechanisms.
Storage conditions
Store at a temperature of 15 to 25 ° C.