Sulfadimethoxine pills 500mg №10

Pills

Composition

1 pill contains sulfadimetoksina 500 mg.

Packing

10 pieces.

Mechanism of action

Antibacterial agent, sulfonamide derivative. Sulfadimethoxin has a long lasting effect when taken orally. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines.

Indications and usage

Infectious and inflammatory diseases caused by microorganisms sensitive to sulfadimethoxine, incl. angina, sinusitis, otitis media, bronchitis, dysentery, inflammatory diseases of the biliary and urinary tract, erysipelas, wound infections, trachoma.

Contraindications

Hypersensitivity to sulfonamides, inhibition of bone marrow hematopoiesis, renal and / or liver failure, chronic heart failure, congenital deficiency of glucose-6-phosphate dehydrogenase, porphyria, azotemia, pregnancy.

Dosage and administration

Sulfadimethoxine accept inside.Accept every 24 h: in the 1st day - 1-2 g, in the subsequent - 0.5-1 g / day; children - 25 mg / kg / day on the first day and 12.5 mg / kg / day - in the next.

Adverse reactions

From the side of the central nervous system: possible headache.

On the part of the digestive system: dyspeptic symptoms, nausea, vomiting, cholestatic hepatitis.

Allergic reactions: skin rashes, drug fever.

On the part of the blood system: rarely - leukopenia, agranulocytosis.

Storage conditions

In the dark place at a temperature of no higher than 20 ° C.