Klimonorm dragee №21

Clemonorm/Klimonorm

Composition and release form

Klimonorm - dragee:

1 yellow bean contains estradiol valerate 2 mg, levonorgestrel 0.15 mg, excipients: lactose monohydrate; potato starch; polyvidone 25,000; talc; Magnesium stearate; sucrose; glucose syrup; gelatin; macrogol 35000; Calcium carbonate; titanium dioxide E171; iron oxide yellow; iron oxide red; iron oxide brown; carnauba wax;

1 brown bean contains estradiol valerate 2 mg, levonorgestrel 0.15 mg, excipients: lactose monohydrate; potato starch; polyvidone 25,000; talc; magnesium stearate; sucrose; glucose syrup; gelatin; macrogol 35000; calcium carbonate; titanium dioxide E171; iron oxide yellow; iron oxide red; iron oxide brown; carnauba wax;

in a blister with a calendar scale of 21 pcs. (9 yellow and 12 brown dragee); in a cardboard box 1 blister.

pharmachologic effect

Klimonorm has anti-menopausal effect.

Indications

Hormone replacement therapy in pre- and postmenopause, incl. after surgical removal of the ovaries;

menopausal syndrome (mental and autonomic symptoms) in peri-and postmenopause;

atrophy of the skin and mucous membranes (including urinary organs) in postmenopause;

signs of irritation of the bladder and urethra,urinary incontinence in a stressful situation (with atrophy of the sphincters of the bladder) in postmenopausal women;

prevention of postmenopausal osteoporosis.

Contraindications

Hypersensitivity to the components of Klimonorm;

severe dysfunction and liver tumors (including history);

congenital disorders of lipid metabolism;

thromboembolic processes (including in the anamnesis);

myocardial infarction;

acute cerebrovascular accident;

hormone-dependent tumors of the uterus, ovaries and mammary glands or suspicion of them;

endometriosis and pathological genital bleeding;

diabetes mellitus (severe), diabetic angiopathy;

idiopathic jaundice, pruritus, herpes, progressive otosclerosis during a previous pregnancy;

pregnancy;

lactation.

Side effects

Rarely can be:

On the part of the digestive tract organs: during the first cycles of treatment, gastrointestinal disorders, nausea, and vomiting are possible.

On the part of the genitourinary system: irregular, enhanced and prolonged vaginal bleeding.

On the part of the skin: pigmentation on the skin (chloasma), itching.

Other: breast tenderness, libido weakening.

Interaction

The activity is reduced by drugs that accelerate the biotransformation of steroid hormones: barbiturates, non-narcotic analgesics (phenylbutazone), antibiotics (rifampicin, ampicillin, Tetracycline, griseofulvin), antiepileptic drugs (carbamazepine, phenytoin).

Dosage and administration

Klimonorm taken orally, pills swallow whole, washed down with a small amount of liquid. The time of day when a woman takes Climonorm does not matter, however, if she started taking pills at any particular time, she should stick to that time and beyond. If a woman has forgotten to take pills, she can take it over the next 12-24 hours. If the treatment is interrupted for a longer time, vaginal bleeding may occur.

If the patient continues to have menstruation, treatment should begin on the 5th day of the menstrual cycle (the 1st day of the menstrual bleeding corresponds to the 1st day of the menstrual cycle). Each package is designed for a 21-day reception. Every day, for the first 9 days, take one yellow dragee, and then, for 12 days, take one brown dragee daily. After a 21-day drug intake, there is a 7-day break in reception, during which menstrual-like bleeding occurs, caused by drug withdrawal (usually 2-3 days after taking the last bean).

After a 7-day break in taking the drug, they start a new package of Climonorm, taking the first pill on the same day of the week as the first pill from the previous pack.

Storage conditions and shelf life

Store in a cool and dark place, protected from light and moisture, at a temperature not higher than 25 ° C. Shelf life - 5 years.