Complivit calcium d3 forte chewable pills №100 mint

Indications

- treatment and prevention of Ca deficiency²⁺ and vitamin D₃:

- osteoporosis: menopausal, senile, "steroid", idiopathic, etc. (prevention and addition to specific treatment);

- osteomalacia (associated with impaired mineral metabolism in patients over 45 years old);

- hypocalcemia (including after adherence to diets with refusal to accept milk and dairy products);

- with an increased need for pregnancy and lactation, as well as in children over 12 years of age during the period of intensive growth.

Dosage and administration

Inside, chew or swallow whole. Doses for adults and children over 12 years old - 1 tab. 2 times a day, in the morning and in the evening, mainly during meals, or individually, depending on the clinical picture.

Adverse effects

Constipation, flatulence, nausea, stomach pain, diarrhea. Hypercalcemia and hypercalciuria. Allergic reactions.

Contraindications

- hypersensitivity;

- hypercalcemia (including as a result of primary or secondary hyperparathyroidism);

- hypercalciuria;

- Calcium nephrolourithiasis;

- hypervitaminosis D;

- sarcoidosis;

- osteoporosis due to immobilization;

- Phenylketonuria (contains aspartame);

- pulmonary tuberculosis (active form).

With caution used in renal failure, benign granulomatosis, during pregnancy, during lactation, simultaneously with the administration of glycosides and thiazide diuretics, in children (up to 12 years).

Use during pregnancy and lactation

With caution used during pregnancy, during lactation. During pregnancy, the daily dose should not exceed 1500 mg of Ca²⁺ and 600 IU of vitamin D₃.

Overdose during pregnancy can lead to impaired mental and physical development of the child.

Ca²⁺ and vitamin D₃ penetrate into breast milk.

Application for violations of kidney function

With caution used in renal failure.

Use in children

With caution used in children (up to 12 years).

Special notes

During the treatment period, Ca excretion must be continuously monitored²⁺ with urine and Ca concentration²⁺ and creatinine in plasma (in the case of calciuria, exceeding 7.5 mmol / day (300 mg / day), you must reduce the dose or stop taking).

Contains aspartame, which is metabolized in the body to phenylalanine, which must be considered in patients suffering from phenylketonuria.

In order to avoid overdose, it is necessary to consider the additional intake of vitamin D₃ from other sources. Do not use simultaneously with vitamin complexes containing Ca²⁺ and vitamin D₃.

Elderly people need Ca²⁺ makes 1.5 g / days, in vitamin D₃ - 0.5-1 thousand IU / day.

Overdosage

Symptoms (after taking 200 chewable tablets): thirst and polyuria (as signs of CRF), loss of appetite, nausea, vomiting, constipation, dizziness, weakness, headache, fainting,coma; with prolonged use: calcification of blood vessels and tissues. Laboratory indicators for overdose: hypercalciuria, hypercalcemia (Ca²⁺ in plasma about 2.6 mmol).

Treatment: rehydration, "loop" diuretics, GCS, calcitonin, bisphosphonates, diet with Ca restriction²⁺conducting hemodialysis.

Drug interaction

Reduces the absorption of bisphosphonates, sodium fluoride and tetracyclines (the interval between intake is at least 2-3 hours).

Increases the risk of developing cardiac glycoside toxicity (ECG and patient condition monitoring is necessary).

Phenytoin, barbiturates, corticosteroids reduce the effect of vitamin D₃, vitamin A - toxicity.

GCS reduces the absorption of Ca²⁺.

Kolestiramin, laxatives (liquid paraffin) reduce the absorption of vitamin D.

Thiazide diuretics increase the risk of hypercalcemia.

Furosemide and other “loop” diuretics increase the excretion of Ca²⁺ by the kidneys.