Sporobacterin Suspension 10ml

Active ingredient and dosage form

Sporobacterin is a biomass suspension of live bacilli Bacillus subtilis 534, white or slightly yellow in color with a specific odor and salty taste, on settling a loose sediment of different shades from white to light brown is formed, which is broken when shaken.
One ml contains at least 1x10⁹ CFU

Pharmacology

Bacillus subtilis strain 534 bacteria secrete a broad-spectrum antibacterial agent that suppresses the development of pathogenic and conditionally pathogenic bacteria. The growth of saprophytes, including normal intestinal microflora, is not inhibited by sporobacterin.
The culture of Bacillus subtilis strain 534 also produces other physiologically active substances of different nature, such as proteolytic enzymes, lysozyme, lipases, amylases, and others, contributing to the breakdown of carbohydrates, fats and proteins, participating in the digestion and assimilation of food. In addition, bacterial enzymes help clean wounds and inflammatory foci from necrotic tissue. The drug has a pronounced stimulating effect on the absorption and digesting activity of phagocytic blood cells.

Indications and usage

Sporobacterin is prescribed to children over 1 year old and adults:

• for the treatment of acute bacterial intestinal infections, including acute dysentery, salmonellosis, etc.
• for the treatment of dysbacteriosis after bacterial infections with the use of antibiotics;
• for the treatment of surgical infection of soft tissue;
• for the treatment of osteomyelitis (in the absence of large sequesters);
• for the prevention and treatment of complications caused by pathogenic and conditionally pathogenic microorganisms during surgical and obstetric-gynecological operations.

Dosage and administration

Treatment of acute intestinal infections:
children from 1 to 3 years old - 0.5 ml, 2 times a day;
children over 3 years old and adults 1 ml 2 times a day for 7-10 days;

Treatment of dysbacteriosis of various etiologies:
children - 0.5 ml 2 times a day for 20 days;
adults - 1 ml 2 times a day for 20 days.

For the treatment of surgical infection Sporobacterin administered 1 ml 2 times a day for 7-10 days.

For prophylactic purulent-septic complications in the postoperative period the drug is prescribed - 5 ml 1 time per day (overnight) for 5 days before surgery and 5 ml 1 time per day (overnight) for 5 days after surgery or injury.

The simultaneous use of antibiotics and sulfonamides can reduce the therapeutic efficacy of sporobacterin.
If necessary, treatments can be repeated.

Before taking Sporobacterin diluted in 10 times the volume of cooled boiled water.
Sporobacterin is taken 30-40 minutes before meals.

An opened vial of the drug, closed with a lid, can be stored in the refrigerator for no more than 10 days.

Adverse reactions

In rare cases, the occurrence of side effects in the form of chills, skin rashes. With a decrease in dosage or withdrawal of the drug, these phenomena are completely inhibited during the day.

Contraindications

The drug should be used with caution in drug allergies.
The effect of the drug on pregnant women has not been studied.

Storage conditions

Store at temperatures from 0 to 8 ° C.