Etacizin pills 50mg №50

Composition

Etacizin - coated tablets: 1 table. contains Etacizin (diethylaminopropionethoxycarbonylaminophenothiazine hydrochloride) 50 mg

excipients: potato starch; sucrose; methylcellulose; Calcium stearate;

in the package of blister strip 10 pcs.; in a carton pack 5 packs.

Mechanism of action

Etacizin has an antiarrhythmic effect.

Indications and usage

Supraventricular and ventricular premature beats;

paroxysms of atrial fibrillation and flutter;

ventricular and supraventricular tachycardia, incl. and in Wolf-Parkinson-White syndrome (WPW).

Indications for use are limited to the presence of severe organic heart disease.

Contraindications

Increased individual sensitivity to etatsizinu;

pronounced conduction disorders (including sinoatrial block, AV block II and III degree in the absence of an artificial pacemaker, violation of intraventricular conduction);

severe left ventricular myocardial hypertrophy;

the presence of postinfarction cardiosclerosis;

cardiogenic shock;

severe hypotension;

chronic heart failure II and III functional class;

severe disorders of the liver and / or kidneys;

pregnancy;

lactation period;

children's age (up to 18 years) - efficiency and safety have not been established;

simultaneous administration of MAO inhibitors;

simultaneous use with antiarrhythmic agents 1C (moracizin (etmozin), propafenon, Allapinin) and IA class (quinidine, procainamide, dnsopyramide, aymalin);

any form of cardiac arrhythmia in conjunction with blockades of the His-Purkinje system.

Adverse reactions

From the side of the cardiovascular system: stop of the sinus node, AV block, violation of intraventricular conduction, reduction of myocardial contractility, reduction of coronary blood flow, arrhythmia development of heart failure).

Changes on an ECG: lengthening of an interval of PQ, expansion of a tooth P and the QRS complex.

From the side of the central nervous system: dizziness, headache, staggering when walking or turning the head, slight drowsiness; in some cases - diplopia, accommodation paresis.

On the part of the digestive tract: nausea.

Perhaps a decrease in side effects or their disappearance after the use of Etacizin for 3-4 days. With long-term treatment with Etacizin, they do not increase, and with the discontinuation of the drug, they quickly disappear. Side effects depend on the size of the dose and, to avoid them, you should not prescribe the maximum dose of the drug.

Dosage and administration

Etacizin taken by mouth, regardless of the meal. The initial dose is 50 mg (1 tab.) 2-3 times a day.With insufficient clinical effect, the dose is increased (under the obligatory ECG control) to 50 mg 4 times a day (200 mg) or 100 mg 3 times a day (300 mg).

Upon reaching a persistent antiarrhythmic effect, maintenance therapy is carried out in individually selected minimum effective doses.

Storage conditions

The drug should be stored out of reach of children at a temperature not exceeding 20 ° C.