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Cosmetic brands
Afrin Spray nasal extra 0.05% 15ml
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Release form, composition and packaging
The drug is approved for use as a means of OTC Spray nasal 1 ml
Oxymetazoline hydrochloride 500 mcg
15 ml - plastic bottles with dosing device (1) - packs of cardboard.
pharmachologic effect
Adrenomimetic agent for local use. Has a vasoconstrictor effect. Intranasal administration reduces swelling of the mucous membrane of the upper respiratory tract. When instilled into the conjunctival sac reduces the swelling of the conjunctiva.
Pharmacokinetics
The effect is manifested 15 minutes after application and lasts for 6-8 hours.
Indications for use of the drug Afrin Extra, spray called. 0.05% 15ml
Obstruction of nasal breathing with colds, inflammation of the sinuses, Eustachitis, hay fever, allergic rhinitis, congestion and conjunctival edema.
Dosage regimen of drug Afrin Extra, spray called. 0.05% 15ml
Apply topically.
Side effect of the drug Afrin Extra, spray called. 0.05% 15ml
On the part of the respiratory system: transient dryness and burning of the mucous membrane of the nasal passages, dry mouth and throat, sneezing; with prolonged use may cause reactive hyperemia of the mucous membrane, atrophy of the mucous membrane.
Since the cardiovascular system: heartbeat; rarely, arterial hypertension.
On the part of the central nervous system: increased irritability, dizziness, headache, sleep disturbances; with prolonged use - tachyphylaxis.
On the part of the digestive system: nausea.
On the part of the organ of vision: with conjunctival administration, mydriasis, accommodation paresis, irritation of the conjunctiva and surrounding tissues, retraction of the eyelid are possible.
Contraindications drug Afrin Extro, called spray. 0.05% 15ml
Inflammation of the mucous membrane of the nasal passages without secretion, chronic heart failure, hyperthyroidism, diabetes mellitus, pregnancy, children under 6 years old (for eye drops), hypersensitivity to oxymetazoline, atrophic rhinitis, lactation, arrhythmias, marked atherosclerosis, arterial hypertension, chronic renal failure closed angle glaucoma.
Use during pregnancy and lactation
Oxymetazoline is contraindicated for use during pregnancy and lactation (breastfeeding).
Application for violations of kidney function
Contraindicated in chronic renal failure.
Use in children
Contraindicated in children under 6 years of age (for eye drops).
Special notes
In the recommended dosage without consultation with your doctor you can use no more than 3 days. Avoid getting the drug intended for intranasal administration in the eyes.
Influence on ability to drive motor transport and control mechanisms
The drug has an effect on vision, possibly reducing the reaction rate.
Drug interaction
With the simultaneous appointment of MAO inhibitors and tricyclic antidepressants may increase blood pressure.
Oxymetazoline slows down the absorption of local anesthetic drugs, prolongs their action.
Co-administration of other vasoconstrictor drugs increases the risk of side effects.