Dayvoneks ointment 30g

ointment

Composition

1 g of ointment for external use contains:

- Active substances
- Calcipotriol 50 mcg.

- Excipients Disodium edetate, sodium hydrogen phosphate,? -Tocopherol, liquid paraffin, polyethylene glycol stearate, propylene glycol, white paraffin, water.

Packing

In a tube of aluminum 30 g ointment for external use. In the package 1 tube.

Mechanism of action

Dayvoneks ointment - a drug for the treatment of psoriasis.

Calcipotriol is a synthetic analogue of the active metabolite of vitamin D, stimulates morphological differentiation and inhibits the proliferation of keratinocytes, which underlies its therapeutic effect in psoriasis.

Calcipotriol is a potent inhibitor of T-lymphocyte activation caused by interleukin I.

The effect of calcipotriol on Calcium metabolism is 100 times weaker than vitamin D 3.

Indications and usage

- Psoriasis vulgar (including chronic psoriasis of the scalp).

Contraindications

- Diseases involving a violation of calcium metabolism.
- Hypersensitivity to the drug.

With caution should use the drug in the following cases:

- Hypercalcemia.
- Hypercalciuria.
- Hypervitaminosis D.
- Nephrolithiasis.
- in children under the age of 6 years - in the appointment of the ointment due to lack of experience with the application.
- In patients older than 65 years.

Pregnancy and Breastfeeding

Do not use Dayvoneks during pregnancy and lactation. The safety of the drug during pregnancy and lactation has not been established. It is not known whether calcipotriol is excreted in breast milk.

Ointment is applied with a thin layer on the affected skin 2 times / day. The therapeutic effect is usually observed after 1-2 weeks from the start of treatment. Duration of treatment is no more than 6-8 weeks.

- For adults, the maximum daily dose is 15 g, the maximum dose per week is not more than 100 g.
- For children over the age of 12, the maximum dose per week is 75 g.
- For children aged 6 to 12 years, the maximum dose per week is not more than 50 g.

Special notes

It is not recommended to apply ointment to the skin.

To avoid contact of the drug with the skin of the face, hands should be thoroughly washed after each use of the ointment.

Hypercalcemia develops when the maximum dose of calcipotriol for the week is exceeded. With the abolition of the drug, the concentration of calcium in the blood quickly normalizes.

Dayvonex treatment can be combined with PUVA therapy.

- Influence on the ability to drive vehicles and control mechanisms Dayvoneks does not affect the ability to drive vehicles and control mechanisms.

Dayvoneks should not be used simultaneously with topical preparations containing salicylic acid.

Overdosage

- Symptoms: when using the drug in doses exceeding the recommended, it is possible to increase the concentration of calcium in the blood.
- Treatment: drug withdrawal.

Storage conditions

- The drug should be stored at a temperature not higher than 25 ° C.