Buy Human immunoglobulin for the / in the use of 5% 25ml
  • Buy Human immunoglobulin for the / in the use of 5% 25ml

Human immunoglobulin for the/in the use of 5% 25ml

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Human immunoglobulin normal for intravenous administration

Characteristic
The drug is an immunologically active protein fraction isolated from human blood plasma of healthy donors, individually tested for the absence of antibodies to human immunodeficiency virus (HIV-1 and HIV-2) and hepatitis C virus and hepatitis B surface antigen (HBsAg).
The drug has a low anticomplementary activity as a result of processing a small amount of pepsin in a weakly acidic medium, followed by the removal of the enzyme aluminum hydroxide.

Description
The drug is a clear or slightly opalescent colorless liquid with a protein concentration of 4.5% to 5.5%. Does not contain preservatives and antibiotics.

Biological and immunological properties
The active component of the drug are immunoglobulins with the activity of antibodies of different specificity. The drug also has non-specific activity, manifested in increasing the resistance of the organism.

Indications
Treatment of severe toxic forms of bacterial and viral infections, postoperative complications, accompanied by septicemia in children and adults.

Dosage and administration
For kids a single dose of the drug is 3-4 ml / kg body weight, but not more than 25 ml.Immediately before administration, the preparation is diluted with sterile 0.9% sodium chloride solution or 5% glucose solution at the rate of: 1 part of the preparation and 4 parts of solvent. Diluted Immunoglobulin is administered intravenously in a drip at a rate of 8–10 drops per minute. Infusions are carried out daily for 3-5 days.
For adults single dose of the drug is 25-50 ml. Immunoglobulin (without additional dilution) is administered in / in the drip at a rate of 30-40 drops per minute. Faster administration may cause a collaptoid reaction. The course of treatment consists of 3-10 transfusions carried out in 24-72 hours (depending on the severity of the disease).
Immunoglobulin for IV injection is used only in a hospital while observing all the rules of asepsis. Before introduction, the vials are kept at a temperature of 20 ± 2 ° C for at least 2 hours. Muddy and solutions containing sediment are not to be used.

Interaction with other drugs
Transfusion therapy with IV immunoglobulin can be combined with the use of other drugs.

Side effects
Reactions to the introduction of immunoglobulin, as a rule, are absent. Individuals with altered reactivity may develop allergic reactions of various types, and in extremely rare cases - anaphylactic shock, and therefore those who received the drug must be under medical supervision. In the room where the drug is injected, anti-shock therapy should be available.

Contraindications
Immunoglobulin is not administered to persons with a history of allergic reactions to blood products. In cases of severe sepsis, the only contraindication for administration is anaphylactic shock on a history of blood preparations. For persons suffering from allergic diseases (bronchial asthma, atopic dermatitis, recurrent urticaria) or prone to allergic reactions, the drug is administered against the background of antihistamines. It is recommended to continue their introduction within 8 days after the end of the course of treatment. In the period of aggravation of the allergic process, the drug is administered at the conclusion of an allergist for health reasons.
Persons suffering from diseases in the genesis of which are the leading immunological mechanisms (collagen, immune blood diseases, nephritis), the drug is prescribed after consulting the appropriate specialist.
The drug is used only on prescription.
Introduction Iimmunoglobulin register in the established accounting forms with the number of the series, date of manufacture, expiration date, the manufacturer, date of administration, dose and nature of the reaction to the introduction of the drug.

Release form
In vials of 25 ml.

Storage and transportation conditions
The drug is stored and transported at a temperature of from 2 to 8 ° C. Freezing is not allowed