Licopid pills 1 mg №10

Active ingredient

white round without shell.
1 pill contains N-acetylglucosaminyl-N-acetylmuramyl-L-alanyl-D-isoglutamine - 1 or 10 mg;
in a blister strip package 10 pcs.; in a carton pack 1 pack.

Mechanism of action

Lycopid is an immunomodulatory drug. It is the main structural unit of the bacterial cell wall. It has the ability to affect the main cell populations of the immune system (macrophages, T-cells and B-lymphocytes), which is probably due to the presence of specific intracellular receptors for glucosaminylmuramyl dipeptide.
By acting on monocyte-macrophage cells, Licopid leads to their activation, enhances the expression of HLA-DR antigens, phagocytosis, increases the activity of lysosomal enzymes, the production of reactive oxygen species, and therefore increases the cytotoxic effect of macrophages against bacterial agents, infected and tumor cells. Under the influence of Licopid, the secretory activity of macrophages is stimulated, which manifests itself in an increase in the synthesis of anti-inflammatory cytokines (interleukin-1, tumor necrosis factor alpha and colony-stimulating factors). These cytokines increase the efficiency of phagocytosis, promote the activation, proliferation and differentiation of T and B lymphocytes,enhancing the synthesis of immunoglobulins, cytotoxicity of lymphocytes, natural killer cells, macrophages. An increase in the synthesis of colony-stimulating factors contributes to the stimulation of leukopoiesis.
It has been established that with the use of high doses of Licopid, a limitation of the biological activity of these cytokines and a decrease in the intensity of the inflammatory process are noted.
It was established that Licopid stimulates antitumor immunity, which is associated with the induction of the cytotoxic properties of lymphocytes and monocyte-macrophage cells.

Secondary immunodeficiencies manifested in chronic, sluggish, recurrent infectious-inflammatory processes of any localization (as part of combination therapy).
Tablets 1 mg and 10 mg (for adults):
- With chronic infections of the upper and lower respiratory tract (for the treatment of exacerbations and prevention of relapse);
- in acute and chronic purulent-inflammatory diseases of the skin and soft tissues (including for the treatment and prevention of purulent-septic postoperative complications);
- with pulmonary tuberculosis;
- with herpetic eye disease;
- with the defeat of the cervix with human papillomavirus;
- with various forms of psoriasis.
Tablets 1 mg (for children :)
- With acute and chronic inflammatory diseases of the skin and soft tissues;
- in case of chronic infections of the upper and lower respiratory tract, both in the acute stage and in the remission stage;
- With a herpetic infection of any localization;
- With chronic viral hepatitis B and C.

Contraindications

 
- pregnancy;
- Individual intolerance to the drug.

Dosage and administration

Licopid is administered orally 30 minutes before a meal (10 mg tablets) and sublingually (1 mg tablets).
In chronic infections of the upper and lower respiratory tract in the acute stage Licopid administered sublingually 1-2 mg 1 time / day for 10 days.
For the prevention of exacerbations of chronic infections of the upper and lower respiratory tract with a prolonged, often recurrent course Likopid appoint inside 5-10 mg 1 time / day for 10 days.
For the prevention of postoperative complications Licopid administered sublingually 1-2 mg 1 time / day for 5-10 days.
For the treatment of purulent-septic processes of the skin and soft tissues of moderate severity (including postoperative) Licopid administered sublingually 2 mg 2-3 times / day for 10 days.
For the treatment of severe forms of purulent-septic processes of the skin and soft tissues Likopid appoint inside 10 mg 1 time / day for 10 days.
With pulmonary tuberculosis Likopid appoint inside 10 mg 1 time / day for 10 days.
With herpetic eye disease administered orally 10 mg 2 times / day for 3 days. After a break of 3 days, the treatment is repeated.
With the defeat of the cervix with human papillomavirus Likopid appoint inside 10 mg 1 time / day for 10 days.
For the treatment of psoriasis with a moderate lesion area Licopid administered orally at a dose of 10 mg 1-2 times / day for 10 days and then every other day at 10-20 mg for the next 10 days, with large area of ​​destruction - inside 10 mg 2 times / day for 20 days.

Licopid is prescribed orally in the form of 1 mg tablets.
In the treatment of chronic infections of the respiratory tract and inflammatory diseases of the skin Licopid administered orally at a dose of 1 mg 1 time / day for 10 days.
When treating a herpes infection the drug is administered orally at a dose of 1 mg 3 times / day for 10 days.
In the treatment of chronic viral hepatitis B and C - by mouth in a dose of 1 mg 3 times / day for 20 days.
Breast children with a protracted course of infectious diseases (including pneumonia, bronchitis, enterocolitis, sepsis, postoperative complications) Licopid administered orally at a dose of 500 mg 2 times / day for 7-10 days.

Adverse reactions

Maybe: in some cases - an increase in body temperature to 37.9 ° C (is short-term, passes on its own and does not require discontinuation of the drug).

Pregnancy and breastfeeding

The use of the drug during pregnancy is contraindicated.
AT experimental studies no embryotoxic, teratogenic and mutagenic action of Licopid was noted.

Special notes

The use of the drug Licopid as part of complex therapy allows to increase the effectiveness of antibacterial, antifungal, antiviral therapy, reduce the duration of treatment and reduce the dose of chemotherapeutic drugs.

Drug Interactions

With simultaneous use of Licopid increases the clinical efficacy of antibacterial, antiviral and antifungal drugs.

Storage conditions

Store in a dry, cool, dark place.