Magnerot pills 500mg №20

Active ingredient and dosage form

Pills flat cylindrical, white with risk on one side.
1 pill contains Magnesium orotate 500 mg (which corresponds to 32.8 mg of magnesium);
Excipients: polyvinylpyrrolidone; talc; magnesium stearate; sodium cyclomate; corn starch; lactose;
in the blister 10 pcs.; in a box of 2 or 5 blisters.

Mechanism of action

Magnerot is a magnesium drug.
Magnesium is an essential macronutrient. Necessary to ensure many energy processes, is involved in the metabolism of proteins, fats, carbohydrates and nucleic acids.
Magnesium takes part in the process of neuromuscular stimulation, inhibiting neuromuscular transmission. Magnesium is of particular interest as a natural physiological Calcium antagonist. Magnesium controls the normal functioning of myocardial cells; involved in the regulation of the contractile function of the myocardium. In stressful situations, an increased amount of free ionized magnesium is removed, and therefore the additional amount of magnesium contributes to an increase in resistance to stress.
The composition of the drug Magnerot includes orotic acid, which promotes cell growth, is involved in the process of metabolism. In addition, orotic acid is necessary for fixing magnesium on ATP in the cell and the manifestation of its action.

Indications and usage

As part of complex therapy and for the prevention of the following diseases:
- myocardial infarction;
- chronic heart failure;
- magnesium-dependent cardiac arrhythmias;
- spastic conditions (including angiospasm);
- atherosclerosis;
- hyperlipidemia.

Contraindications

 
- urolithiasis disease;
- renal dysfunction.

Dosage and administration

Assign 2 tab. 3 times / day for 7 days, then 1 tab. 2-3 times a day. The duration of treatment is at least 4-6 weeks. The question of conducting repeated courses of treatment is decided individually.
When night cramps calf muscles It is recommended to take 2-3 tab. drug.
Tablets should be taken with a small amount of liquid.

Adverse Effects

Gastrointestinal: erratic stools and diarrhea (when taking the drug in high doses), which usually go away on their own at lower doses.

Pregnancy and breastfeeding

It is possible to use Magnerot during pregnancy and lactation (breastfeeding) according to indications, since during these periods the need for magnesium increases significantly. If its content is not balanced, then this can lead to serious complications, including miscarriage.

Special notes

Magnerot can be used for a long time. It should be borne in mind that gastrointestinal diseases can lead to magnesium deficiency in the body; food consumption with reducedmagnesium content; chronic alcoholism (due to the reduction of magnesium reabsorption in the renal tubules and increased excretion of magnesium from the body); taking certain medications (oral contraceptives, diuretics, muscle relaxants, glucocorticoids, insulin); conditions requiring increased magnesium intake (physical inactivity, stress, pregnancy).

Overdosage

Symptoms: may increase the manifestations of the described side effects.

Drug Interactions

At the same time taking magnesium, which is part of Magnerot, complicates the absorption of iron, Tetracycline and sodium fluoride, and therefore the interval between taking these drugs should be 2-3 hours.

The drug should be stored at a temperature not exceeding 25 ° C, out of the reach of children.