Formula of calmness pill №40

Composition

Active ingredients: motherwort extract dry with a total content of flavonoids in terms of rutin 1.0% - 50.0 mg, Magnesium asparaginate tetrahydrate - 250.0 mg (equivalent to magnesium content (Mg ++) 17 mg), Pyridoxine hydrochloride (vitamin B6) - 1.0 mg.

Auxiliary components: microcrystalline cellulose - 170.9 mg, maltodextrin - 37.3 mg, croscarmellose sodium - 27.5 mg, colloidal silicon dioxide - 5.5 mg, Calcium stearate - 4.1 mg, potato starch - 3.7 mg.

Auxiliary components of the pill shell: hypromellose (hydroxypropyl methyl cellulose) - 8.7 mg, titanium dioxide - 6.28 mg, macrogol-4000 (polyethylene glycol 4000) - 4.83 mg, talc - 0.19 mg.

pharmachologic effect

The formula of tranquility® has a sedative, anti-anxiety effect, without causing drowsiness, lethargy and addiction. It has anti-stress effect, improves the tolerance of psycho-emotional stress.

Pharmacological activity of the drug due to its constituent active ingredients, providing a comprehensive effect on the nervous system:

Motherwort dry extract has a sedative effect, as well as moderate cardiotonic (slows down the rhythm and increases the strength of heart contractions) and moderate hypotensive action.

Magnesium is an indispensable element, is contained in all cells and tissues of the body, it is necessary for the normal functioning of the nervous, cardiovascular and digestive systems. Participates in neuromuscular transmission, protein synthesis.

Magnesium deficiency is manifested in the form of neuromuscular disorders (muscle weakness, tremors, cramps, convulsions), mental disorders (insomnia, irritability, anxiety), heart rhythm disorders (extrasystole, tachycardia).

Pyridoxine hydrochloride (vitamin B6) is necessary for the normal functioning of the central and peripheral nervous system, as well as contributes to a more complete and rapid absorption of magnesium. It plays an important role in the metabolism, has an effect on erythropoiesis.

Indications

• neurotic and neurosis-like reactions, accompanied by increased nervous irritability, irritability, anxiety, fear;
• sleep disorders (insomnia), manifested by a violation of sleep, intermittent superficial sleep, premature waking up;
• as part of complex therapy for neurocirculatory dystonia.

Contraindications

Increased individual sensitivity to the components of the drug, gastric ulcer and duodenal ulcer in the acute phase, children under 18 years of age, phenylketonuria, severe renal failure (creatinine clearance less than 30 ml / minute).

Use during pregnancy and lactation

The drug is not recommended to be taken during pregnancy and during breastfeeding, due to the lack of sufficient experience of clinical use in this category of patients.

special instructions

Before you start using the drug, you should consult with your doctor.

The drug is not recommended for use in children under 18 years due to the lack of clinical studies.

When taking the drug in patients with impaired renal function, it is necessary to monitor the concentration of magnesium in the blood serum.

Influence on ability to steer vehicles, mechanisms

During the period of use of the drug, care should be taken when performing potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (driving and other vehicles, working with moving mechanisms).

Dosage and administration

Inside 1 pill 2 times a day with meals. For sleep disorders: by mouth 1 pill 30 minutes before bedtime. The course of treatment is determined by the doctor taking into account the course of the disease and is up to 4 weeks. Repeated courses of treatment are possible on the recommendation of a doctor.

Side effects

Allergic reactions to the components of the drug, dyspepsia (abdominal pain, nausea, heartburn, flatulence, diarrhea, constipation) are possible. In the event of any adverse events, the use of the drug should be discontinued and consult your doctor.

Drug interaction

The drug enhances the action of hypnotic drugs and other drugs that depress the central nervous system, antihypertensive drugs.

The simultaneous use of drugs containing phosphates or calcium salts, can significantly reduce the absorption of magnesium in the gastrointestinal tract.

Magnesium preparations reduce the absorption of Tetracycline, it is recommended to take the drug with an interval of 3 hours after taking the antibiotic.

Magnesium weakens the action of oral thrombolytic agents, reduces the absorption of iron.

Pyridoxine hydrochloride (vitamin B6) inhibits the activity of Levodopa.

Overdosage

Possible symptoms of overdose: fatigue, dizziness, hand tremor, abdominal pain of a spastic nature. If the above symptoms occur, it is necessary to wash the stomach and consult a doctor.

Storage conditions

At a temperature not higher than 25 ºС.

Keep out of the reach of children.