Sulfacyl sodium tube-dropper 20% - 2 ml №2

Latin name

SULFACYL SODIUM

Active substance

Sulfacetamide

Release form

eye drops

International Classification of Diseases (ICD-10)

A54.3

Gonococcal infection of the eye

H01.0

Blepharitis

H10.2

Other acute conjunctivitis

H10.4

Chronic conjunctivitis

H16.0

Corneal ulcer

Pharmacological group

Antimicrobial drug for topical use in ophthalmology

Mechanism of action

Antibacterial agent for local use in ophthalmology, sulfanilamide derivative. It has a wide spectrum of antimicrobial action. It has a bacteriostatic effect. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines.

Sulphacetamide is active against gram-positive and gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp., Actinomyces spp.

Pharmacokinetics

When applied topically penetrates the tissues and eye fluids. It is absorbed into the systemic circulation through the inflamed conjunctiva.

Indications

Purulent corneal ulcers, conjunctivitis, blepharitis, gonorrheal eye diseases in newborns and adults, prevention of necrosis in newborns.

Contraindications

Hypersensitivity to sulfacetamide and other sulfanilamide drugs.

Side effects

Local reactions: itching, redness, swelling.

Special notes

Patients who are hypersensitive to Furosemide, thiazide diuretics, sulfonylurea or carbonic anhydrase inhibitors may be hypersensitive to sulfacetamide.

Drug interaction

When applied locally, sulfacetamide is incompatible with silver salts.

Mode of application

Apply 2-3 drops to the lower conjunctival sac of each eye 5-6 times / day.

To prevent blistering in newborns, 2 drops of the solution are instilled into the eyes immediately after birth and 2 drops after 2 hours.