

Mechanism of actionAntihypoxic agent, has antioxidant, metabolic, vasodilating and hypotensive action. Increases the efficiency of tissue respiration under hypoxic conditions, especially in organs with a high content of metabolism (brain, cardiac muscle, liver). It provides a reduction in oxygen consumption with significant physical exertion, improving tissue respiration, reducing mental and physical fatigue, performing labor-intensive physical operations. Optimizes the activity of the mitochondria of cells, reduces their oxygen consumption. It has powerful electron-acceptor properties, acts directly on the mitochondrial respiratory chain. The presence of a thiosulfate group in the polymer structure provides an antiradical and antioxidant effect. Indications and usageSevere traumatic lesions, blood loss, extensive surgical intervention (as part of complex therapy). Inside - extreme and unfavorable conditions, accompanied by a lack of oxygen: high mountains, polar conditions, underwater work (to improve the performance of the body); overwork, fatigue, mental and physical overstrain, increased stress, operator activity. In / in slowly, with a speed of 40-60 drops / min, in a single dose of 0.14 g (1 ampoule) 1-3 times a day at regular intervals. Before use, the contents of the ampoule is diluted in 500 ml of infusion fluid (5% dextrose solution). The course of treatment is 3-5 days. Inside, before meals or with meals with a small amount of water. Single dose for adults - 0.5-1 g, daily - 1.5-3 g; for children, a single dose - 0.25 g, daily - 0.75 g. The course of treatment is 3-14 days, depending on the conditions in which the body is to be, or the severity of the patient's condition. Adverse reactionsAllergic reactions, drowsiness, dry mouth, nausea, abdominal pain. With rapid on / in the introduction - lowering blood pressure. Overdose: depression of the respiratory center. ContraindicationsHypersensitivity, pregnancy, lactation, hemorrhagic stroke. |