Buy Sermion coated tablets 10mg №50
  • Buy Sermion coated tablets 10mg №50

Sermion pills 10mg №50

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Indications

- acute and chronic cerebral metabolic and vascular disorders (due to atherosclerosis, arterial hypertension, thrombosis or embolism of cerebral vessels, including acute transient cerebral circulation, vascular dementia (30 mg pills should be used) and vasospasm headache );

- acute and chronic peripheral metabolic and vascular disorders (organic and functional arteriopathy of the extremities, Raynaud's disease, syndromes caused by impaired peripheral blood flow).

Dosage and administration

The drug is administered orally for 5-10 mg 3 times / day or 30 mg 2 times / day, at regular intervals, for a long time.

At chronic cerebrovascular accident, vascular cognitive impairment, post-stroke conditions Sermion® appoint 10 mg 3 times / day. The therapeutic effect of the drug develops gradually, and the course of treatment should be at least 3 months.

At vascular dementia appoint 30 mg 2 times / day. In this case, the patient is advised to consult with the doctor every 6 months about the advisability of continuing therapy.

At acute disorders of cerebral circulation, ischemic stroke due to atherosclerosis, thrombosis and embolism of cerebral vessels, transient disturbances of cerebral circulation (transient ischemic attacks, hypertensive cerebral crises) It is preferable to start the course of treatment with parenteral administration of Nicergoline, then continue taking the drug inside.

At peripheral circulatory disorders Sermion ® appoint 10 mg 3 times / day for a long time (up to several months).

Have patients with impaired renal function (serum creatinine ≥2 mg / dL) Sermion® recommended for use in lower therapeutic doses.

Adverse effects

Cardiovascular: pronounced decrease in blood pressure (mainly after parenteral administration), dizziness, and a sensation of heat.

Nervous system: confusion, headache, drowsiness or sleeplessness.

Gastrointestinal: dyspeptic symptoms, abdominal discomfort, diarrhea, constipation, nausea.

Metabolism: possible increase in the concentration of uric acid in the blood, and this effect does not depend on the dose and duration of therapy.

Other: skin rashes.

Contraindications

- recently suffered acute myocardial infarction;

- acute bleeding;

- severe bradycardia;

- violation of orthostatic regulation;

- deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption;

- children's and teenage age up to 18 years;

- pregnancy;

- lactation period (breastfeeding);

- Hypersensitivity to nicergoline, other ergotamine derivatives, auxiliary components of the drug.

WITH caution should be used for hyperuricemia or gout in history and / or in combination with drugs that violate the metabolism and / or excretion of uric acid.

Use during pregnancy and lactation

Due to the lack of special studies, the use of the drug during pregnancy is contraindicated.

At the time of taking the drug, you must abandon breastfeeding, because Nicergoline and its metabolic products are excreted in breast milk.

Application for violations of kidney function

Have patients with impaired renal function (serum creatinine ≥2 mg / dL) Sermion® recommended for use in lower therapeutic doses.

Use in children

The drug is contraindicated in children and adolescents under 18 years of age.

Special notes

In therapeutic doses Sermion®As a rule, it does not affect blood pressure, but in patients with arterial hypertension it can cause a gradual decrease in blood pressure.

The drug acts gradually, so it should be taken for a long time, while the doctor should periodically (at least every 6 months) evaluate the effect of treatment and the appropriateness of its continuation.

Influence on ability to drive motor transport and control mechanisms

Despite the fact that Sermion® helps to improve concentration of attention, the effect of the drug on the ability to drive vehicles and work with mechanisms has not been specifically studied.Given the nature of the underlying disease, patients should exercise caution in potentially hazardous activities.

Overdosage

Symptoms: a pronounced decrease in blood pressure.

Treatment: Special treatment is usually not required, it is enough for the patient to take a horizontal position for several minutes. In exceptional cases, with a sharp disturbance in the blood supply to the brain and the heart, the introduction of sympathomimetic drugs under the constant control of blood pressure is recommended.

Drug interaction

With simultaneous use of Sermion® may enhance the effect of antihypertensive drugs.

Nicergoline is metabolized by the action of CYP2D6 isoenzyme, therefore the possibility of Sermion's interaction with drugs cannot be ruled out., which are metabolized with the participation of the same enzyme.

With simultaneous use of nicergoline with Acetylsalicylic acid may increase bleeding time.

Pharmacy sales terms

Terms and conditions of storage

The drug should be stored out of reach of children at a temperature not exceeding 25 ° C.