Novanefron pills №30

Release form

Tablets 30 pcs.

Pharmacology

Staminus orthosiphon (orthosiphon stamineus benth). The leaves of ortosiphon contain glycoside orthosifonin (0.01%), alkaloids, fatty oils (2.7%), tartaric acid (1.5%), citric acid, essential oils (0.2–0.66%), saponins, after saponification of which α-amyrin, β-sitosterol and tannin are released. In medicine, orthophiphon drugs are used as a diuretic in acute and chronic kidney diseases, accompanied by edema, albuminuria, azotemia, and kidney stone disease. The diuretic effect is accompanied by increased excretion of urea, uric acid and chlorides from the body. Ortosiphon increases the secretion of gastric glands and free hydrochloric acid. Ortosiphon has low toxicity, has a wide breadth of therapeutic action and with long-term use does not cause side effects.

Bearberry (Arctostaphylos uva-ursi L.). Bearberry leaves contain flavanoids (quercetin, isoquercetin, myricitrin, hyperoside, miracetin), organic acids (malic, protocatex, formic), pyrogallic tannins, arbutin glycosides, and methylarbutin. All of these active ingredients form the basis of the chemical composition of bearberry (bear's ear).

Herbal medicines bearberry have anti-inflammatory, antimicrobial and diuretic properties.Anti-inflammatory effect of the drug due to the content of a large number of tannins. The antimicrobial property of the plant is associated with the glycoside arbutin, which, under the influence of the enzyme arbutase contained in the leaves, is broken down into free hydroquinone and glucose. The second glycoside, methylarbutin, by hydrolysis, cleaves methyl alcohol, releases hydroquinone. The antiseptic properties of bearberry leaves are due to the antimicrobial and local irritating effects of hydroquinone, which, excreted in the urine through the kidneys, irritates the kidney tissue and increases urination.

Cranberry (cranberry juice). Contains: organic acids (including benzoic), pectic substances, triterpene compounds, flavanoids, anthocyanins, catechins, tannins, vitamin C, carotenoids. Cranberries are also rich in potassium and iron. Cranberry has antimicrobial properties, including against staphylococci, streptococci, Escherichia coli, Proteus, cholera pathogens. Antifungal action noted. In addition, cranberries enhance the action of antibiotics, nitrofurans and sulfa drugs, in particular, in the treatment of pyelonephritis and gynecological inflammatory diseases. Currently, cranberries are recommended for use in urinary tract infections. An interesting property of the cranberry fruit extract was found to counteract adhesion and adhesion of bacteria to the cells of the mucous membrane of the urinary bladder, which prevents them from forming colonies.One of the components contained in the cranberry fruit, ursuloic acid, has a strong diuretic effect and prevents the formation of kidney stones.

Horsetail (equiseum) used as a diuretic, hemostatic, hypotensive, anti-inflammatory, anti-sclerotic agent. The 5-glucoside-luteolin isolated from the horsetail has antimicrobial and anti-inflammatory properties. Horsetail extract optimizes water-salt metabolism and improves the condition for diseases of the urinary system. During urate-acid diathesis, the active substances of the horsetail keep the balance between colloids and crystalloids in the urine and, thereby, inhibit the formation of urinary stones, especially oxalates. Silicon compounds of the plant play an important role in the metabolism and functional activity of the connective tissue of the joints and the walls of blood vessels.

Corn silk (Zea mays L - com silk). Bitter glycosidic substances 1.15%, saponins 3.18%, fatty oils 2.5%, cryptosanthin, ascorbic and pantothenic acid, vitamin K, inositol, sitosterol, stigmasterol were found in the corn stigmas. Corn seeds contain starch 61.2%, corn oil, a large amount of pentosans 7.4%, biotin, nicotinic and pantothenic acid, quercetin, isoquercetin, etc. Corn silk are used as a diuretic, choleretic, hemostatic agent in the treatment of cholecystitis, with urological diseases, urolithiasis, nephritis, edema, as well as with worm infestations.

Blueberry (Vaccinium mytillus). Blueberry leaves are rich in inulin, flavonoids, anthocyanins. Fruits contain carbohydrates, organic acids, Vitamins (C, B1, B2, P, PP), carotene, a high amount of phenoxyacids (quinic, coffee, chlorogenic), manganese and iron compounds. Bilberry is known as enhancing the body's immunity, its resistance to stress, hemostatic, hematopoietic, vasodilator, astringent, choleretic and diuretic.

Dandelion officinalis (Taraxacum officinale). Dandelion roots contain taraxacin up to 10%, triterpene compounds (taraxerol, taraxasterol), sterols (p-sitosterol, stigmasterol), flavonoids (cosmosine, luteolin-7-glucoside), inulin up to 24%, fatty oils, sucrose up to 20%, proteins 15%, carotene, tannins, essential oils. Dandelion roots contain alcohols, saponins, significant amounts of protein, vitamins C, A, B₂, nicotinic acid. The content of iron, Calcium, manganese and phosphorus found in dandelion leaves is higher than in leafy vegetables. The roots and leaves have anti-inflammatory, choleretic, diuretic, diuretic, expectorant, antipyretic, laxative, antiallergic and antihelminthic action.

Magnesium citrate supports the necessary energy level of the whole organism. It is recommended for muscle weakness, nervous exhaustion, general fatigue and chronic fatigue syndrome. With a lack of Magnesium, potassium is excreted from the body, which leads to fatigue, loss of strength and weakness in the heat.In addition, 80–90% of intracellular magnesium is found in combination with ATP, which is a universal carrier and the main energy accumulator in living cells. Magnesium maintains the urine salts in a dissolved state and prevents their precipitation. Suppresses stone formation in the kidneys, even in low concentrations crystallization inhibits. Mg ions²⁺ bind in the urine to 40% of oxalic acid. Prevents precipitation of calcium compounds. It is an antidote for poisoning with salts of heavy metals.

Indications

• Acute and chronic inflammatory diseases of the urinary organs (urethritis, cystitis, pyelonephritis, vulvitis, vaginitis);
• kidney stones (nephrolithiasis) and bladder stones;
• chronic viral hepatitis;
• nephrotic syndrome;
• arterial hypertension;
• in case of cardiovascular insufficiency of II-III degree (together with cardiac glycosides);
• cholecystitis, cirrhosis, ascites, helminthic invasions.

Contraindications

• Hypersensitivity to the drug;
• hyperacid gastritis;
• peptic ulcer of the stomach or duodenum against the background of increased acidity of the gastric juice;
• increased blood clotting.

Pregnanacy and breastfeeding

Since biologically active food supplements have free use by consumers, Novanefron is not advised to use pregnant women without the advice of a doctor. The doctor, having determined the need of arbutinin and hydrochonin in a pregnant woman, may prescribe Novanefron. The use of Novanefron during pregnancy is possible only in the II and III trimester.

Active ingredient

Active substances: staminus ortosiphon (orthosiphon stamineus benth) 80 mg; bearberry ordinary (80 mg); cranberry (cranberry juice) 80 mg; corn silk (com silk) 80 mg; horsetail (equiseum) 40 mg; bilberry ordinary (dandelion) 40 mg; Dandelion officinalis (bilberry common) 40 mg; magnesium citrate 20 mg.

Dosage and administration

With free use by the consumer, it is necessary to comply with the rules that are listed on the packaging. If the drug is prescribed by a doctor, a change in dosage is possible. 1-2 pills twice a day, morning and evening. The duration of treatment is 2-8 weeks.

Adverse effects

Novanefron is usually well tolerated. Seldom: allergic reactions, weakness.

Storage conditions

Store at a temperature not exceeding 25 ° C.