Buy Nicorette chewing gum 2mg №30 frosty mint
  • Buy Nicorette chewing gum 2mg №30 frosty mint

Nicorette chewing gum 2mg №30 frosty mint

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Mechanism of action

Nicorette chewing gum frost mint - a drug for the treatment of nicotine addiction. After abrupt smoking cessation, patients who use nicotine-containing products for a long period of time may develop withdrawal syndrome, which includes dysphoria, insomnia, irritability, anxiety, impaired attention, decreased heart rate, increased appetite and weight gain, and also desire to smoke.

When treating nicotine addiction, nicotine replacement therapy can reduce the need for smoking (and the number of cigarettes smoked), reduce the severity of withdrawal symptoms that arise when you quit smoking completely. It facilitates temporary abstinence from smoking and helps to reduce the number of cigarettes smoked by those who are unable or unwilling to completely quit smoking.

Indications

For the treatment of tobacco addiction:

- reduction of withdrawal symptoms that occur when patients completely quit smoking, who have decided to quit smoking;

- in case of temporary cessation of smoking;

-To reduce the number of cigarettes smoked for those who can not or do not want to completely stop smoking.

Contraindications

Hypersensitivity to nicotine and other components of the drug.

Use during pregnancy and lactation

Nicotine penetrates the placental barrier and can have a negative effect on the respiratory system and fetal circulation. Smoking can cause serious harm to the fetus, so patients should try to convince about the need to quit smoking without using replacement therapy with nicotine-containing drugs. With the failure of such attempts, the decision to conduct therapy is made after comparing the possible positive effect and potential harm.

Nicotine (even when used in therapeutic doses) in small quantities penetrates into breast milk and may have an adverse effect on an infant when taking the drug by a nursing mother. In order to reduce the negative effects of nicotine on a child, Nicorette should be used immediately after feeding.

Special notes

Use of the drug Nicorette® accompanied by less risk than smoking.

The patient should be informed that he should wear a chewing gum. Nicorette® with him to use it if he suddenly wants to smoke.

Patients with diabetes after smoking cessation may require a decrease in insulin doses.

Patients with impaired chewing function are encouraged to use other dosage forms.

Use in pediatrics

Experience with Nicorette® in adolescents younger than 18 years old is absent, so the drug should be used strictly as prescribed by a doctor.

Influence on ability to drive motor transport and control mechanisms

Negative impact on the ability to drive a car and work with mechanisms is not installed.

Composition

Nicotine 2 mg

Excipients: chewing gum base, powdered sorbitol, sorbitol solution (crystallizing), glycerol solution 85%, sodium carbonate, flavoring 84.6422, flavoring Haverstroo ZD49284, FDA-certified dye quinoline yellow D & C №10.

Dosage and administration

Depending on the severity of addiction to smoking, use Nicorette chewing gum with different concentrations of the active substance. If the patient smokes 20 or less cigarettes per day or smokes the first cigarette 30 minutes after waking up, then chewing gum with a nicotine content of 2 mg should be used. If a patient smokes more than 20 cigarettes per day or he was unable to quit smoking when using chewing gum with a nicotine content of 2 mg, then it is recommended to use chewing gum with a nicotine content of 4 mg.

Nicorette should be used in all cases where there is an irresistible desire to smoke. The gum should be chewed slowly until a sharp taste appears, then chewing should be stopped and the gum should be placed between the gum and the inside of the cheek. After the disappearance of taste should resume chewing.For 1 reception, only 1 chewing gum should be used.

With a complete cessation of smoking, the average daily dose is 8-12 gum, the maximum - 15 gum. It is necessary to continuously use the drug in the first 3 months after quitting. Then you should gradually reduce the number of consumed gum. When the daily intake of the drug is reduced to 1-2 gum, its use should be discontinued. However, you should always keep in stock some amount of the drug, because suddenly there may be a desire to smoke.

When reducing the number of cigarettes smoked, chewing gum should be used between smoking episodes to lengthen the intervals between smoking cigarettes in order to minimize cigarette consumption. The patient should be warned that if after 6 weeks of using the drug it was not possible to achieve a reduction in daily cigarette consumption, you should consult a specialist doctor.

The patient should try to quit smoking when he is ready for this, but not later than 6 months after the start of treatment. If it was not possible to quit smoking within 9 months after the start of therapy, you should consult a specialist.

Nicorette chewing gum is not recommended for more than 12 months. However, some patients may require longer treatment to prevent a return to smoking or not to return to previous levels of tobacco consumption.

Chewing gum can be used during periods when you need to temporarily stop smoking, for example, when you are in places where it is forbidden to smoke, or in other situations when you need to refrain from smoking.

Side effects

In the recommended dose of Nicorette® does not cause serious adverse effects. At the beginning of treatment, nicotine contained in chewing gum can sometimes cause mild throat irritation and increased salivation, and if an excessive amount of dissolved nicotine is swallowed, a hiccup is possible.

With excessive use of the drug by persons who are not accustomed to inhaling tobacco smoke, nausea, weakness, and headache are possible (similar to the symptoms that occur in these patients when tobacco smoke is inhaled).

From the side of the central nervous system: very often - headache; often dizziness.

Cardiovascular: sometimes - rapid heartbeat; very rarely - atrial rhythm disturbances.

On the part of the digestive system: very often - gastrointestinal discomfort, hiccups, nausea; often - vomiting.

Dermatological reactions: sometimes - erythema, urticaria.

Others: very often - sore throat or mouth, pain in the masticatory muscles; rarely, allergic reactions, including angioedema.

Some symptoms, such as dizziness, headache, sleep disturbances, can be manifestations of withdrawal caused by quitting smoking. When you quit smoking, the incidence of aphthous stomatitis may increase.

When using chewing gum with a nicotine content of 4 mg in patients prone to indigestion, slight digestive disorders or heartburn are possible. Usually, this problem is eliminated by slower chewing gum or using gum containing 2 mg of nicotine (if necessary with a smaller interval).

Drug interaction

Smoking (but not the use of nicotine) causes an increase in CYP1A2 activity. After cessation of smoking, a decrease in the substrate clearance of this enzyme can be observed, which can lead to an increase in the concentration of certain drugs in the blood plasma, which has potential clinical significance with the simultaneous use of drugs characterized by a small breadth of therapeutic action (theophylline, tacrine, clozapine, ropinirole).

Limited evidence suggests that smoking may induce the metabolism of flekainida and pentazocine.

Overdosage

Symptoms: nausea, drooling, abdominal pain, diarrhea, sweating, headache, dizziness, hearing loss, and severe general weakness; in severe cases, arterial hypotension, weak and irregular pulse, difficulty breathing, vascular collapse and generalized seizures, i.e. symptoms of acute nicotine poisoning.

Doses of nicotine, which are well tolerated in the course of treatment by adult smokers, can cause symptoms of severe poisoning in young children and even be fatal.

Treatment: You should immediately stop taking nicotine and start symptomatic treatment. Activated carbon reduces the absorption of nicotine in the digestive tract. If necessary, appoint IVL and oxygen.

Storage conditions

The drug should be stored out of reach of children at a temperature not exceeding 25 ° C.