Erispirus pills prolonged 80mg №30

Pharmachologic effect.
Bronchodilating, anti-asthma, anti-inflammatory, antihistamine.
It blocks histamine H1 receptors, is an antagonist of inflammatory mediators (serotonin, histamine, bradykinin), has papaverine-like antispasmodic effect. In high doses, it reduces the production of pro-inflammatory agents (cytokines, tumor necrosis factor alpha, arachidonic acid metabolites, free radicals), some of which have a bronchoconstricting effect. In experimental studies, the likelihood of a teratogenic effect (the development of the “wolf mouth”) was found.
Well absorbed from the gastrointestinal tract, Cmax is achieved after 6 hours (tablets) or 2.3 hours (syrup); T1 / 2 - 12 hours. It is mainly excreted by the kidneys (90%) and the intestines (10%).
Indications for use of the drug
Rhinopharyngitis, laryngitis, otitis media, sinusitis, rhinotracheobronchitis, bronchitis, supportive therapy of isolated and complicated bronchial asthma, respiratory symptoms in measles, whooping cough, flu.
Dosing regimen of the drug
Is ingested before meals. Adults - 80 mg 2-3 times / day; children - 4 mg / kg / day.
Side effect of the drug
Possible: moderately pronounced dyspeptic phenomena, nausea, epigastric pain, drowsiness.
Rarely: moderate tachycardia.
Contraindications drug Erispirus, pills p / pl / o prolong 80mg number 30 to use.
Hypersensitivity to fenspiride, pregnancy, lactation, children under 14 years of age (for tablets).
Use during pregnancy and lactation.
Fenspiride is contraindicated for use during pregnancy and lactation (breastfeeding).
Use in children.
Contraindicated in children under 14 years of age (for tablets).
Special instructions.
Fenspiride treatment does not replace antibacterial therapy and cannot serve as a reason for postponing the adequate prescription of antibacterial drugs.
Storage conditions.
At temperatures not above 25 ° C.
Keep out of the reach of children.