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Odeston pills 200mg №100
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Active substance
Hymekromon
Composition
Tablets from white to white with a yellowish shade of color, round, flat-cylindrical, with a chamfer and engraved on one side with the letters "Ch".
1 tab.:
Gimekromon 200 mg
Excipients: potato starch - 45 mg, gelatin - 3 mg, sodium lauryl sulfate - 1 mg, Magnesium stearate - 1 mg.
Mode of application
The drug is used inside for 30 minutes before eating.
Adults appoint 200-400 mg 3 times / day. The daily dose is 1200 mg. The course of treatment is 2 weeks.
In case of missing a dose, you must take the drug as soon as possible. If the time of the next intake is approaching, you should not take the missed dose. You should not take a double dose of the drug in order to compensate for the missed.
Overdosage
Currently, cases of overdose Odeston not reported.
Side effects
On the part of the digestive system: diarrhea, flatulence, abdominal pain, ulceration of the gastrointestinal mucosa.
Other: allergic reactions, headache.
Indications
- dyskinesia of the biliary tract and the sphincter of Oddi in hyperkinetic type;
- non-calculous chronic cholecystitis, cholangitis, cholelithiasis;
- condition after surgery on the gallbladder and biliary tract;
- loss of appetite, nausea, constipation, vomiting (against the background of bile hyposecretion).
Contraindications
- obstruction of the biliary tract; - renal failure;
- liver failure;
- ulcerative colitis;
- Crohn's disease;
- gastric ulcer and duodenal ulcer;
- hemophilia;
- children's and teenage age up to 18 years;
- hypersensitivity to the drug.
Special notes
Special precautions when disposing of unused medication
Do not throw medicines into sewers or into household waste containers. For information on how to dispose of unused medication, please contact your pharmacist. These activities will help protect the environment.
Influence on ability to drive motor transport and control mechanisms
The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require high concentration of attention and speed of psychomotor reactions.
Mechanism of action
Clinico-pharmacological group: A drug with choleretic and antispasmodic action
Pharmaco-therapeutic group: Choleretic agent
pharmachologic effect
Choleretic drug. Increases the formation and secretion of bile. It has a selective antispasmodic effect on the bile ducts and the sphincter of Oddi. The drug does not reduce gastrointestinal peristalsis and blood pressure.
Reduces the stagnation of bile, prevents the crystallization of cholesterol and, thereby, the development of cholelithiasis.
Pharmacokinetics
Suction and distribution
After ingestion is rapidly absorbed from the gastrointestinal tract. Cmax in the blood after ingestion is achieved in 2-3 hours. It is poorly bound to plasma proteins.
Removal
T1 / 2 is about 1 hour. Excreted in the urine: about 93% - as glucuronate, 1.4% - as sulfonate, 0.3% - unchanged.
Shelf life
3 years
Storage conditions
At temperatures not above 25 ° C.