Calcium gluconate pills 500mg №20

Mechanism of action

Calcium is a macro element involved in the formation of bone tissue, the process of blood coagulation, is necessary to maintain stable cardiac activity, the processes of transmission of nerve impulses. Improves muscle contraction in muscular dystrophy, myasthenia, reduces vascular permeability. With the on / in the introduction of Calcium causes the excitation of the sympathetic nervous system and increased release of adrenaline by the adrenal glands; has a moderate diuretic effect.

Indications

Hypocalcemia of various genesis, hypoparathyroidism, parenchymal hepatitis, toxic liver damage, nephritis, eclampsia, hyperkalemic form of paroxysmal myoplegia, inflammatory and exudative processes, skin diseases. As an additional tool in the treatment of allergic diseases and drug allergies. As an additional hemostatic agent for pulmonary, gastrointestinal, nasal, uterine bleeding. As an antidote for poisoning with Magnesium salts, oxalic acid and its soluble salts.

Dosage and administration

For ingestion a single dose - 1-3 g, the multiplicity of reception - 2-3. With intravenous or intramuscular injection of Calcium gluconate solution, a single dose of the drug should correspond to 2.25-4.5 mmol of calcium.Calcium chloride solution is administered intravenously in a jet (slowly) in a single dose of 500 mg, in intravenous drip in a single dose of 0.5-1 g.

Side effect

Maybe: nausea, vomiting, diarrhea, bradycardia; with the / m introduction - necrosis.

Contraindications

Hypercalcemia, severe hypercalciuria, severe renal failure, tendency to thrombosis, hypersensitivity to calcium gluconate.

Application for violations of kidney function

Contraindicated in severe renal failure.

It is used with caution in patients with a small hypercalciuria, with minor impaired renal function or with a history of urolithiasis; in these cases, urinary calcium excretion should be regularly monitored. Patients with a tendency to the formation of stones in the urine is recommended to increase the volume of fluid intake.

Use in children

It is not recommended to enter the / m children.

Special notes

It is used with caution in patients with a small hypercalciuria, with minor impaired renal function or with a history of urolithiasis; in these cases, urinary calcium excretion should be regularly monitored. Patients with a tendency to the formation of stones in the urine is recommended to increase the volume of fluid intake.

It is not recommended to enter the / m children.

Drug interaction

Calcium gluconate with simultaneous use reduces the effect of calcium channel blockers.In / in the introduction of calcium gluconate before or after Verapamil reduces its hypotensive effect, but does not affect its antiarrhythmic effect. Under the influence of Kolestiramin calcium absorption from the gastrointestinal tract is reduced. With simultaneous use with quinidine may slow intraventricular conductivity and increase the toxicity of quinidine. During treatment with cardiac glycosides, parenteral administration of calcium gluconate is not recommended, due to increased cardiotoxicity. With simultaneous oral administration of calcium gluconate and tetracyclines, the action of the latter may decrease, due to a decrease in their absorption.