Vesicare pills coated 5mg №30

Vesicare)

Composition and release form

Vesicare - coated tablets:

1 pill contains solifenacin succinate 5 and 10 mg; 10 and 30 pieces per pack.

Pharmacology

Vesicare has a spasmolytic, anticholinergic effect.

Indications

urgent (imperative) urinary incontinence;

frequent urination and urgent (imperative) urge to urinate, characteristic of patients with overactive bladder syndrome.

Contraindications

hypersensitivity to the drug;

urinary retention;

severe gastrointestinal diseases (including toxic megacolon);

myasthenia gravis;

angle-closure glaucoma;

hemodialysis;

severe liver failure;

severe renal impairment or moderate hepatic impairment with simultaneous treatment with strong CYP3A4 inhibitors, such as Ketoconazole.

Pregnanacy and breastfeeding

There is no clinical data on women who become pregnant while taking solifenacin. Animal studies have not revealed a direct adverse effect on fertility, embryo / fetus development or childbirth. Care should be taken when prescribing this drug to pregnant women.

There are no data on the excretion of solifenacin with milk in humans. Application Vesicare is not recommended during breastfeeding.

Adverse Effects

Vesicare may cause side effects associated with the anticholinergic action of solifenacin, often with mild or moderate severity. The frequency of these adverse effects is dose dependent. The most frequently observed side effect of Vesicare is dry mouth. It was observed in 11% of patients receiving a dose of 5 mg per day, in 22% of patients receiving a dose of 10 mg per day, and in 4% receiving placebo. The severity of dry mouth was usually mild and only in rare cases led to interruption of treatment. In general, compliance (compliance) was very high.

Dosing regimen

Inside, drinking liquid, regardless of the time of a meal, 5 mg 1 time per day. If necessary, the dose of Vesicare can be increased to 10 mg once a day.

Special notes

Before starting treatment with Vesicare, it should be ascertained whether there are other reasons for increased urination (heart failure or kidney disease). If a urinary tract infection is detected, appropriate antibacterial treatment should be initiated.

Storage conditions and shelf life

To store a preparation in the dry, protected from light place at a temperature not higher than 25C. Shelf life 2 years.