Atrovent n aerosol 20 μg/dose vial 10 ml 200 doses

Composition

Atrovent N metered dose inhalation:
1 ml of solution contains 0,021 mg ipratropium bromide;
in aerosol cans with a mouthpiece of 10 ml (200 doses); in the box 1 cylinder

Mechanism of action

Atrovent - bronchodilator drug - blocker of m-cholinergic receptors. It blocks the m-cholinergic receptors of the smooth muscles of the bronchi (mainly at the level of the large and medium bronchi) and suppresses reflex bronchoconstriction. Having a structural similarity with the acetylcholine molecule, is its competitive antagonist.

Warns bronchospasm resulting from inhalation of cigarette smoke, cold air, the action of various drugs, and also eliminates bronchospasm associated with the influence of the vagus nerve.

Indications and usage

Chronic obstructive pulmonary disease (chronic obstructive bronchitis, pulmonary emphysema); bronchial asthma (moderate and mild), especially with concomitant diseases of the cardiovascular system.

Contraindications

Hypersensitivity to atropine and its derivatives, and other components of the drug, pregnancy (I term), children under 6 years old (Atrovent H).

Dosage and administration

Adults and children over 6 years old - 2 doses of aerosol 4 times a day, if necessary, the dose can be increased to 12 inhalations per day.

Pregnancy and Breastfeeding

Contraindicated in the first trimester of pregnancy, the appointment of Atrovent is possible in the II-III trimester of pregnancy and during breastfeeding only if the expected effect of therapy outweighs the potential risk to the fetus or child.

Adverse reactions

The most frequent undesirable effects are headache, nausea, dry mouth.
Due to the low systemic absorption of the drug, side effects associated with systemic anticholinergic effects, such as tachycardia, palpitations, accommodation disturbances, decreased secretion of sweat glands, impaired gastrointestinal motility, urinary retention, are rare and are reversible. However, in patients with obstructive lesions of the urinary tract, the risk of urinary retention increases.

Special notes

Atrovent H is not recommended for emergency relief of asthma attack (the bronchodilator effect develops later than that of beta-adrenostimulants).
Patients with cystic fibrosis have an increased likelihood of slowing gastrointestinal motility.

In the dark place at a temperature of no higher than 25 ° C.