Buy Dynamic forward film dispersing 100mg №2
  • Buy Dynamic forward film dispersing 100mg №2

Dinamico pills film dispersing 100mg №2

$45.31
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Composition

1 film contains the active substance: Sildenafil 100 mg

Films dispersed in the mouth - 2 pieces per pack

Mechanism of action

Sildenafil is used to treat erectile dysfunction, restores impaired erectile function under sexual stimulation by increasing blood flow in the penis.

The implementation of the physiological mechanism of erection is associated with the release of nitric oxide (NO) in the cavernous body due to sexual arousal. NO activates the enzyme guanylate cyclase, which leads to an increase in the concentration of cyclic guanosine monophosphate (cGMP). In turn, cGMP causes relaxation of the smooth muscles of blood vessels and, accordingly, blood flow to the cavernous body of the penis.

After ingestion is rapidly absorbed. The maximum concentration in the blood plasma (Cmax) when taken on an empty stomach is reached within 30-120 minutes.

Indications and usage

Treatment of erectile dysfunction, characterized by the inability to achieve or maintain an erection of the penis, sufficient for satisfactory sexual intercourse.

Effective only with sexual stimulation.

Inside, about 1 hour before planned sexual activity. The film is removed from the sachet (bag) with dry hands, immediately placed on the tongue and held until completely dissolved, then swallowed. When taken with meals, the onset of action of the drug DINAMIKO FORWARD may be delayed compared to taking the drug on an empty stomach.

The recommended dose for most adult patients is 50 mg. Taking into account the effectiveness and tolerability, the dose of DINAMIKO FORWARD may be increased to 100 mg or reduced to 25 mg (in this case, another dosage form should be used in a dose of 25 mg). The maximum recommended dose is 100 mg. The maximum recommended frequency of use 1 time per day.

Contraindications

  • Hypersensitivity to sildenafil or any other component of the drug.
  • With the constant or intermittent use of nitric oxide donors (such as coca nitrite), organic nitrates or nitrates in any dosage forms, because sildenafil increases the hypotensive effect of nitrates.
  • Use in patients for whom sexual activity is undesirable (for example, with severe cardiovascular diseases, such as severe heart failure, unstable angina).
  • Transferred in the last six months of cerebral circulation or myocardial infarction.
  • Simultaneous administration of ritonavir.
  • Chronic renal failure severe.
  • Hereditary degenerative diseases of the retina, including retinitis pigmentosa (the smaller part of such patients has a genetic disorder of retinal phosphodiesterase), due to the fact that the safety of use has not been studied.
  • Arterial hypotension (BP less than 90/50 mm Hg)
  • It is not recommended to use simultaneously with other agents for the treatment of erectile dysfunction (the safety and efficacy of combination therapy has not been studied).
  • According to the registered offer is not intended for use in women and children under 18 years.

Special notes

Erectile dysfunction treatments should be used with caution in patients with anatomical deformation of the penis (angulation, cavernous fibrosis, Peyronie's disease), or in patients with risk factors for priapism (sickle cell anemia, multiple myeloma, leukemia).

In the post-marketing period, cases of prolonged erection and priapism were reported. If an erection persists for more than 4 hours, seek medical attention. If priapism therapy is not carried out in a timely manner, it can lead to damage to the tissues of the penis and irreversible loss of potency.

Drugs intended for the treatment of erectile dysfunction should not be used in men for whom sexual activity is undesirable.

Sexual activity poses a certain risk in the presence of heart disease, so before starting any therapy for erectile dysfunction, the doctor should refer the patient to an examination of the cardiovascular system.Sexual activity is undesirable in patients with heart failure, unstable angina, suffered myocardial infarction or stroke in the last 6 months, life-threatening arrhythmias, arterial hypertension (BP greater than 170/100 mm Hg) or hypotension (BP less than 90/50 mm Hg). Art.). There is no difference in the incidence of myocardial infarction (1.1 per 100 people per year) or the mortality rate from cardiovascular diseases (0.3 ha 100 people per year) in patients who received sildenafil compared with patients who received placebo.

Storage conditions

Store at a temperature not higher than 25 ° С. Keep out of the reach of children.