Finasteride pills 5mg №30

Coated Tablets

1 coated pill contains 5m finasteride

Packing

30 pieces

Mechanism of action

Finasteride is a synthetic 4-azasteroid compound, a competitive and specific inhibitor of steroid 5-alpha reductase, an intracellular enzyme that turns testosterone into active androgen 5-dihydrotestosterone. The growth of prostate tissue and the development of benign hyperplasia are due to the conversion of testosterone to dihydrotestosterone in the cells of the prostate gland. Under the influence of the drug, there is a significant decrease in the concentration of dihydrosterone in the blood plasma and in the gland tissue. Finastirid does not bind to androgen receptors. As a result of the use of the drug, the size of the prostate gland decreases, the severity of symptoms associated with prostatic hyperplasia decreases. The drug does not affect the plasma lipid concentration, as well as the content in the blood plasma of cortisol, estradiol, prolactin, thyroid stimulating hormone, thyroxin.

Finasteride is indicated for benign prostatic hyperplasia (to reduce the size of the prostate gland,increase the maximum rate of outflow of urine and reduce the symptoms associated with hyperplasia, reduce the risk of acute urinary retention and the associated likelihood of surgical intervention.

Contraindications

Hypersensitivity to finasteride and other components of the drug, prostate cancer, urinary tract obstruction, children's age.

Carefully - abnormal liver function.

Dosage and administration

Finasteride is taken orally, regardless of the meal, 1 pill (5 mg) per day for 6-7 months.

Adverse reactions

Allergic reactions, gynecomastia, breast tenderness, impotence, decreased libido and decreased volume of ejaculate. The frequency of side effects does not exceed 3-4% and decreases during treatment. In some cases, there was an increase in the concentration of luteinizing and follicle-stimulating hormones and testosterone by about 10%, however, these figures remained within normal limits.

Special notes

Before treatment, it is necessary to exclude diseases that can simulate benign prostatic hyperplasia, such as infectious prostatitis, prostate cancer, urethral stricture, bladder hypotension, and a number of changes in the urinary system arising from certain diseases of the nervous system.Since the use of finasteride has a decrease in prostate-specific antigen (by 41% and 48%, respectively, by 6 and 12 months from the start of therapy), periodically during the therapy process, patients should be examined to exclude prostate cancer. Women of childbearing age and pregnant women should avoid contact with the crushed pills of the drug Finasteride, because the ability of the drug to suppress the conversion of testosterone to dihydrotestosterone can cause a violation of the development of the genital organs in the male fetus. Finasteride pills are film-coated and during normal handling, if they are not ground into powder or their integrity is broken, contact with the active substance is excluded.

Storage conditions

In a dry, protected by light and inaccessible to children place, at a temperature not higher than 25 ° C