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Biopokrov mycosis nail polish bottle 6ml
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Description
Cyclopirox (Ciclopirox) has a broad spectrum of antifungal (fungicidal) action. Effective when applied topically with dermatomycetes, yeast-like fungi, molds and other types of fungi. It is active against the main causative agents of onychomycosis, including Trichophyton rubrum, Epidermophyton floccosum, Candida albicans, Scopulariopsis brevicaulis, Microsporum canis, Malassezia furfur, certain strains of bacteria (both gram-positive and gram-negative). It damages the cell wall of the fungus and blocks the transport of potassium ions, phosphates, amino acids. Lacquer is used to treat and prevent fungal infections caused by fungi sensitive to the drug: nail mycoses (onychomycosis). In the form of nail polish quickly (within the first hours after application) and penetrates deep into the nail and is deposited for a long time at the site of infection; The lacquer forms a physical barrier that prevents reinfection.
Clotrimazole (Clotrimazole) has a broad spectrum of antifungal, antibacterial and antiprotozoal effects. Effective against dermatophytes, yeast fungi and mold fungi (of the genus Candida, Torulopsis glabrata, of the genus Rhodotorula, Malassezia furfur), erythrasma, gram-like, гра, om, om, C, C, C Corynebacterium minutissimum) and gram-negative bacteria (ag ag ag ag ag ag ag ag ag is is is is is is is is is is is is is is is is is is is is is is is is om om om om om om om om om om om om om om om om om om om om om om om om om om om om om om om) Violates the synthesis of ergosterol (the main structural component of the cell membrane of fungi), changes the permeability of the membrane of the fungus, promotes the release of potassium from cells, intracellular phosphorus compounds and the breakdown of cellular nucleic acids. Inhibits the synthesis of triglycerides and phospholipids.It reduces the activity of oxidative and peroxidase enzymes, as a result of which the intracellular concentration of hydrogen peroxide rises to a toxic level, which contributes to the destruction of cellular organelles and leads to cell necrosis.
Clotrimazole destroys the cytoplasmic membrane of microorganisms with the formation of vacuoles inside the cell, and also inhibits the synthesis of their nucleic acids and proteins. Clotrimazole acts mainly on growing and dividing microorganisms.
Act
The complex of the active components of lacquer has antifungal, antibacterial and antiprotozoal effects. The combined effect of ciclopirox and clotrimazole provides:
- effective double antifungal action;
- prevents further growth and spread of the fungal infection in the nail;
- protection of nail plates from fungal infections;
Recommendations for use
In order to increase efficiency, it is recommended to remove as much of the nail as possible with signs of fungus damage before the first application of the lacquer and process the rest with a nail file to create an uneven (rough) surface.
The lacquer is applied with a thin layer 1 time per day on the nail with signs of fungal damage during the first month. Once a week, all varnish is removed with a nail polish remover. During the second month, the varnish is applied 2 times a week, during the third month - once a week.
The duration of application depends on the individual growth rate of the nail plate. Varnish is used before the regeneration of the nail and the complete disappearance of signs of infection by a fungus. After the disappearance of signs of fungal infection, the lacquer is used as a protective agent for another 1-2 weeks.
Active ingredients
8% ciclopirox (Ciclopirox), 1% clotrimazole (Clotrimazole).