Valparin XP pills prolonged 300mg №30

VALPARIN HR TAB. PROLONG. 300MG №30

Valparin XP, pills of the prolonged action, film coated.
Latin name: Valparine XR.
Active ingredient: Valproic acid * (Valproic acid *).
ATH: N03AG01 Valproic acid.
Pharmacological group: Antiepileptic drugs.

Release form, composition and packaging:
* pills of prolonged action, coated white, round, biconvex.
--------------------------------------------- 1 tabl.
sodium valproate ------------- 200 mg
valproic acid ------- 87 mg, which corresponds to the total sodium content of valproate 300 mg
Excipients: colloidal silicon dioxide, hydroxypropyl methyl cellulose, ethyl cellulose, silicon dioxide hydrate, sodium saccharin, glycerin, titanium dioxide, E-100 eudragit, NE-30D eudragit, polyethylene glycol 1500, talc.
10 pieces - strips (10) - packs cardboard.

* pills of prolonged action, coated white, oblong, with a notch on both sides.
--------------------------------------------- 1 tabl.
sodium valproate ------------- 333 mg
valproic acid ------- 145 mg, which corresponds to the total sodium content of valproate 500 mg
Excipients: colloidal silicon dioxide, hydroxypropyl methyl cellulose, ethyl cellulose, silicon dioxide hydrate, sodium saccharin, glycerin, titanium dioxide, E-100 eudragit, NE-30D eudragit, polyethylene glycol 1500, talc.
10 pieces - strips (10) - packs cardboard.

Mechanism of action

: 
Anticonvulsant.

Indications and usage

: 
Treatment of generalized or partial epilepsy, especially for the following types of seizures:
- absences;
- myoclonic;
- tonic-clonic;
- atonic.
Partial epilepsy:
- simple or combined seizures;
- secondary generalized seizures.
Specific syndromes (Vesta, Lennox-Gasto).

Dosing regimen:
The dosage regimen is selected individually depending on the age and body weight of the patient.

Adverse reactions

: 
On the part of the digestive system: rarely - nausea, vomiting, diarrhea and / or constipation, hepatitis, pancreatitis.
Allergic reactions: rarely - skin rash, itching, photosensitivity, erythema multiforme, Stevens-Johnson syndrome.
From the side of the central nervous system: rarely - ataxia, tremor, impaired consciousness, coma.
On the part of the reproductive system: rarely - violation of the menstrual cycle, secondary amenorrhea.
On the part of the hematopoietic system: rarely - anemia, thrombocytopenia, neutropenia, leukopenia, a decrease in the content of fibrinogen, inhibition of platelet aggregation.
Other: 2-12% - hair loss; rarely - weight gain, hyperammonemia, creatininemia.

Contraindications

: 
- severe dysfunction of the pancreas;
- acute or chronic hepatitis, cases of active hepatitis in the family history (primarily of medicinal genesis);
- porphyria;
- thrombocytopenia;
- pregnancy;
- lactation (breastfeeding);
- children's age up to 3 years;
- Hypersensitivity to valproic acid and other components of the drug.

Use of the drug VALPARIN® XP during pregnancy and lactation:
Prescribing a drug during pregnancy is possible only when the intended benefit to the mother outweighs the potential risk to the fetus. In the case of taking the drug during pregnancy, it is necessary to conduct specialized prenatal monitoring of the fetus.
The use of the drug during breastfeeding is not recommended.

Application for violations of the liver:
Contraindicated in acute or chronic hepatitis, cases of active hepatitis in the family history (primarily drug origin

Vacation conditions:

Storage conditions:
List B.: In a dry place, at a temperature not higher than 30 ° C. (in closed package)