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Mildronate ampoules 10% 5ml №10
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Mechanism of action
Mildronate - a drug that improves metabolism. Meldonium is a structural analogue of gamma-butyrobetaine, a substance that is found in every cell of the human body.
Under high load conditionsMildronate® restores the balance between the delivery and the need of cells for oxygen, eliminates the accumulation of toxic metabolic products in the cells, protecting them from damage; also has a tonic effect. As a result of its use, the body acquires the ability to withstand the load and quickly restore energy reserves. Thanks to these propertiesMildronate®used for the treatment of various disorders of the cardiovascular system, the blood supply to the brain, as well as increasing physical and mental performance.
As a result of a decrease in the concentration of Carnitine, gamma-butyrobetaine, which has vasodilating properties, is intensively synthesized. In acute ischemic myocardial damageMildronate® slows down the formation of a necrotic zone, shortens the rehabilitation period.
In heart failure, the drug increases myocardial contractility, increases exercise tolerance, and reduces the frequency of strokes.
In acute and chronic ischemic disorders of cerebral circulation improves blood circulation in the ischemic focus, promotes the redistribution of blood in favor of the ischemic area.
Effective with vascular and dystrophic pathology of the fundus.
The drug eliminates functional disorders of the nervous system in patients with chronic alcoholism with withdrawal syndrome.
Indications and usage
- as part of a complex treatment of coronary heart disease (angina, myocardial infarction), chronic heart failure;
- as part of the complex treatment of acute and chronic disorders of cerebral circulation (strokes and cerebrovascular insufficiency);
- reduced performance;
- withdrawal syndrome in chronic alcoholism (in combination with a specific therapy of alcoholism);
- hemophthalmus, retinal hemorrhages of various etiologies;
- Thrombosis of the central vein of the retina and its branches;
- retinopathy of various etiologies (diabetic, hypertensive).
Contraindications
- increased intracranial pressure (including in violation of the venous outflow, intracranial tumors);
- Hypersensitivity to the drug.
WITH caution apply for diseases of the liver and / or kidneys, especially for a long time.
Pregnancy and Breastfeeding
Safety of useMildronata during pregnancy is not proven.In order to avoid possible adverse effects on the fetus, the drug should not be prescribed during pregnancy.
It is not known whether the drug is excreted in breast milk. If necessary, useMildronata during lactation, breastfeeding should be discontinued.
At a temperature not higher than 25 ° С