Combilipen 2ml №10

/Combilipen

Combilipen - solution for intramuscular injection: 1 amp. contains thiamine hydrochloride (Vit. B1) 100 mg, Pyridoxine hydrochloride (Vit. B6) 100 mg, cyanocobalamin (Vit. B12) 1 mg, Lidocaine hydrochloride 20 mg, excipients: benzyl alcohol, sodium tripolyphosphate, sodium phosphate, potassium hexacyanoferrate, sodium hydroxide, water d / i.; Pack of 5 and 10 ampoules.

Mechanism of action

Combined multivitamin preparation. Combilipen action is determined by the properties of Vitamins that make up its composition.

Thiamine hydrochloride (vitamin B1) is involved in conducting nerve impulses.

Pyridoxine hydrochloride (vitamin B6) has a vital effect on the metabolism of proteins, carbohydrates and fats, is necessary for normal blood formation, functioning of the central nervous system and the peripheral nervous system. It provides synaptic transmission, inhibition processes in the central nervous system, participates in the transport of sphingosine, which is part of the nerve sheath, and participates in the synthesis of catecholamines.

Cyanocobalamin (vitamin B12) is involved in the synthesis of nucleotides, is an important factor in the normal growth, blood formation and development of epithelial cells; necessary for folic acid metabolism and myelin synthesis.

Indications and usage

Combilipen is used as part of complex therapy for the following neurological diseases:

- trigeminal neuralgia;

- neuritis of the facial nerve;

- pain syndrome caused by diseases of the spine (intercostal neuralgia, lumbar sciatica, lumbar syndrome, cervical syndrome, cervico-brachial syndrome, radicular syndrome caused by degenerative changes of the spine);

- polyneuropathy of various etiologies (diabetic, alcoholic).

Contraindications

- severe and acute forms of decompensated heart failure;

- pregnancy;

- lactation period (breastfeeding);

- Hypersensitivity to the components of Combilipen.

Adverse reactions

Allergic reactions: pruritus, urticaria, difficulty breathing, angioedema, anaphylactic shock.

Other: increased sweating, tachycardia, acne.

Dosage and administration

Combilipen enter in / m.

When symptoms are expressed, 2 ml is prescribed daily for 5-7 days, then 2 ml 2-3 times / week. within 2 weeks; in mild cases - 2 ml 2-3 times / week. 7-10 days. The duration of treatment is determined by the doctor individually, depending on the severity of the symptoms of the disease, but should not exceed 2 weeks. For maintenance therapy, it is recommended to take oral forms of vitamins of group B.

Storage conditions

In the dark place at a temperature of no higher than 8 ° C. Shelf life - 2 years.