Nystatin ointment 100000ed/1g 15g

Active ingredient and dosage form

Nystatin ointment:
1 g of ointment contains 100 000 IU of nystatna;
in aluminum tubes or orange glass cans of 10, 15 or 30 g.

Pharmacology

Nystatin is a polyene antifungal antibiotic highly active against yeast-like fungi of the genus Candida. It has a fungicidal effect. The structure of the antibiotic has a large number of double bonds with a high tropism for the sterol structures of the cytoplasmic membrane of fungi, which contributes to the incorporation of the drug molecule into the cell membrane and the formation of a large number of channels through which the uncontrolled transport of electrolytes takes place. An increase in osmolarity inside the cell leads to its death.

Indications and usage

Nystatin is used for candidiasis of the mucous membranes of the mucous membranes (mouth, vagina, etc.),
skin and internal organs (digestive tract, lungs, kidneys, etc.)
With the preventive purpose, Nystatin is prescribed to prevent the development of candidiasis with prolonged treatment with antibacterial agents, especially in exhausted and weakened patients.

Contraindications

Hypersensitivity, abnormal liver function, pancreatitis, peptic ulcer and 12 duodenal ulcer, pregnancy.

Dosage and administration

When treating fungal diseases of the skin and mucous membranes, ointment is applied with a thin layer to the affected areas 1-2 times a day, daily for 7-10 days. The use of ointment can be combined with the reception of nystatin inside.

Storage conditions

Store the ointment in a dry, dark place, out of reach of children, at a temperature not exceeding +5 ° C.