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Amlovas pills 5mg №30
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Active ingredient and dosage form
1 pill contains Amlodipine 5 or 10 mg,
in a package of 20, 30 or 100 pcs.
Mechanism of action
Amlovas - antihypertensive, antianginal, antispasmodic, vasodilator. It blocks the entry of Calcium ions through the cell membranes into the smooth muscle cells of the myocardium and blood vessels. Amlovas has a direct relaxing effect on vascular smooth muscle, dilates peripheral arterioles, which leads to a reduction in OPSS, reduces the load on the heart and reduces the myocardial oxygen demand, expands the coronary arteries, increasing the oxygen supply to the myocardium.
Indications and usage
Arterial hypertension (monotherapy and in combination with thiazide diuretics, ACE inhibitors or alpha- and beta-blockers), angina pectoris (stable and unstable, including Prinzmetal or variant), dilated (non-ischemic) cardiomyopathy with a severe form of chronic heart failure.
Dosage and administration
Inside, the initial dose Amlovas 5 mgsv day. If necessary, the daily dose may be increased to 10 mg. The maximum daily dose of 10 mg.
Contraindications
Hypersensitivity, hypotension.
Adverse reactions
From the nervous system and sensory organs: dizziness, headache, drowsiness, feeling tired; rarely - a change in mood, asthenia, convulsions, myalgia,blurred vision, paresthesia.
Since the cardiovascular system and blood (hematopoiesis, hemostasis): heartbeat, hot flashes.
On the part of the digestive tract: nausea, abdominal pain, dyspeptic symptoms; rarely - gingival hyperplasia, increased levels of hepatic transaminases, jaundice.
From the genitourinary system: increased urination, edema, impotence.
For the skin: allergic reactions (skin rash, itching), rarely - erythema multiforme.
Other: rarely - shortness of breath, gynecomastia.
Pregnancy and Breastfeeding
It is possible only if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.
Special notes
It should refrain from the use of Amlovas in pediatric practice, since the safety and efficacy of its use in children have not been determined.
The drug should be stored in a dry, dark place at a temperature not higher than 25 ° C.