Cholitiline Capsules 400mg №14

Indications and usage

Traumatic brain injury (acute period) with predominantly stem-level lesions, chronic cerebrovascular insufficiency (dyscirculatory encephalopathy), dementia (Alzheimer's type, senile, mixed forms), ischemic stroke (recovery period), Gentington's chorea, functional disorders of the CNS, memory impairment, confusion, disorientation, reduced motivation, initiative and concentration, senile pseudomelancholia.

400 mg capsules.

Stimulates cholinergic receptors, mainly central (has a cholinomimetic effect). In the body it splits into choline and glycerol phosphate. Substrately provides the synthesis of acetylcholine and phosphatidylcholine neuronal membranes. Stimulates cholinergic neurotransmission, improves the plasticity of neuronal membranes and the function of receptors, activates cerebral blood flow, stimulates the metabolism of the CNS and the reticular formation. It improves mood, improves mental activity, concentration of attention, memorization and ability to reproduce the received information, optimizes cognitive and behavioral reactions, eliminates emotional instability, apathy.In the acute period of traumatic brain injuries, it helps normalize blood flow and bioelectric brain activity on the affected side, and promotes regression of neurological symptoms.

Oral absorption - 88%; easily penetrates the BBB, accumulates mainly in the brain (concentration in the brain reaches 45% of the level in the blood), lungs and liver; 85% is excreted by the lungs in the form of carbon dioxide, the rest (15%) is excreted by the kidneys and through the intestines.

Does not affect the reproductive cycle, does not possess teratogenic and mutagenic effects.

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, pregnancy, breastfeeding.

Adverse reactions

Nausea, allergic reactions.

Dosage and Administration

The drug should be taken orally, before meals, 400 mg 3 times a day, a course of 3-6 months.