Rispolept pills coated 4mg №20

Rispolept/Rispolept

Composition and release form

Rispolept - coated tablets:

1 tab. contains Risperidone 1, 2, and 3 mg; 20 pieces per pack.

pharmachologic effect

Rispolept has an antipsychotic effect.

Indications

Relief of acute attacks and long-term maintenance therapy of the following conditions:

acute and chronic schizophrenia and other psychotic disorders with productive and negative symptoms;

affective disorders in various mental illnesses;

behavioral disorders in patients with dementia with symptoms of aggressiveness (outbreak of anger, physical abuse), impaired activity (agitation, delirium) or psychotic symptoms;

behavioral disorders in adolescents from 15 years and adult patients with reduced intellectual level or mental retardation, in cases where destructive behavior (aggressiveness, impulsivity, auto-aggression) is leading in the clinical picture of the disease.

Stabilization of mood in the treatment of mania with bipolar disorders - as a means of adjuvant therapy.

Contraindications

individual hypersensitivity to rispolept;

lactation period.

Carefully:

diseases of the cardiovascular system (chronic heart failure, myocardial infarction, cardiac muscle conduction disturbances);

dehydration and hypovolemia;

disorders of cerebral circulation;

Parkinson's disease;

convulsions (including in history);

severe renal or hepatic impairment;

drug abuse or drug dependence;

conditions predisposing to the development of tachycardia of the “pirouette” type (bradycardia, electrolyte imbalance, concomitant medication taking, extending the QT interval);

brain tumor, intestinal obstruction, cases of acute drug overdose, Reye's syndrome - the antiemetic effect of risperidone may mask the symptoms of these conditions;

pregnancy;

children's age up to 15 years (efficiency and safety are not established).

Side effects

On the part of the nervous system: insomnia, agitation, anxiety, headache; sometimes - drowsiness, fatigue, dizziness, impaired concentration, blurred vision; rarely, extrapyramidal symptoms (tremor, rigidity, hypersalivation, bradykinesia, akathisia, acute dystonia), mania or hypomania, stroke (in elderly patients with predisposing factors), as well as hypervolemia (either due to polydipsia, or due to inadequate secretion syndrome ADH), tardive dyskinesia (involuntary rhythmic movements mainly of the tongue and / or face), neuroleptic malignant syndrome (hyperthermia, muscle rigidity,instability of autonomic functions, impaired consciousness and increased creatine phosphokinase levels), impaired thermoregulation and epileptic seizures.

On the part of the digestive system: constipation, dyspepsia, nausea or vomiting, abdominal pain, increased activity of hepatic transaminases, dry mouth, hypo or hypersalivation, anorexia and / or increased appetite, increased or decreased body weight.

Since the cardiovascular system: sometimes - orthostatic hypotension, reflex tachycardia or increased blood pressure.

From the side of blood-forming organs: neutropenia, thrombocytopenia.

On the part of the endocrine system: galactorrhea, gynecomastia, menstrual disorders, amenorrhea, weight gain, hyperglycemia and exacerbation of preexisting diabetes.

On the part of the urogenital system: priapism, erectile dysfunction, ejaculation disorder, anorgasmia, urinary incontinence.

On the part of the skin: dry skin, hyperpigmentation, itching, seborrhea.

Allergic reactions: rhinitis, rash, angioedema, photosensitization.

Others: arthralgia.

Dosage and administration

Rispolept accept inside. The dosage regimen is set individually. Adults and children over 15 years: 1 or 2 times a day. The initial dose is 2 mg / day, on the second day the dose should be increased to 4 mg / day.

Storage conditions and shelf life

In a dry, dark place at a temperature of no higher than 25 ° C. Shelf life - 3 years.