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Gaviscon Mint Chewable pills №24
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Mechanism of action
Antacid medication. After ingestion, the drug quickly interacts with the acidic contents of the stomach. This forms alginate gel, which has an almost neutral pH. The gel forms a protective barrier on the surface of the stomach contents, preventing the appearance of gastroesophageal reflux for up to 4 hours. In the case of regurgitation, the gel is more likely to enter the esophagus, where it reduces irritation of the mucous membrane.
Reduction of irritation of the mucous membrane of the esophagus is felt in 3-4 minutes after taking the drug.
Pharmacokinetics
The drug does not have systemic bioavailability (not absorbed).
Indications
- treatment of symptoms such as sour belching, heartburn, dyspepsia, feeling of heaviness in the stomach, occurring after a meal, in patients with gastroesophageal reflux or during pregnancy.
Dosage and administration
The drug is taken orally. The pill should be thoroughly chewed.
Adults and children over 12 years old appoint 2-4 tab. after meals and before bedtime (up to 4 times / day).
If after 7 days of use, the symptoms persist, the patient should consult a doctor to review the therapy.
Elderly patients dose adjustment is not required.
Patients with impaired liver function dose adjustment is not required.
Patients with impaired renal function when a low salt diet is necessary, the drug should be taken with caution.
Side effect
The frequency of adverse reactions was estimated based on the following criteria: very often (≥1 / 10), often (≥1 / 100, <1/10), infrequently (≥1 / 1000, <1/100), rarely (≥1 / 10 000, <1/1000), very rarely (<1/10 000) and the frequency is unknown (the frequency cannot be calculated from the available data).
Immune system:frequency is unknown - anaphylactic and anaphylactoid reactions, hypersensitivity reactions (urticaria).
Respiratory:frequency is unknown - respiratory effects (bronchospasm).
If any of the side effects indicated in the instructions are aggravated or other side effects that are not indicated in the instructions are noted, the patient should inform the doctor.
Contraindications
- phenylketonuria;
- children's age up to 12 years;
- hypersensitivity to the drug.
with caution the drug should be used for hypercalcemia, nephrocalcinosis and urolithiasis with the formation of oxalate stones, congestive heart failure, impaired renal function. In the presence of these diseases or conditions before using the drug, the patient should consult a doctor.
Use during pregnancy and lactation
Clinical studies involving more than 500 pregnant women and the amount of data obtained in the post-registration period did not show the feto-and neonatal toxicity of the active substances. Gaviscon® can be used during pregnancy with clinical need and after consultation with a doctor.
Gaviscon® can be used during breastfeeding.
Application for violations of the liver
Patients with impaired liver functiondose adjustment is not required.
Application for violations of kidney function
with caution the drug should be used for nephrocalcinosis and urolithiasis with the formation of oxalate stones, impaired renal function.
Use in children
The use of the drug is contraindicated inchildren under 12 years old.
Use in elderly patients
Forelderly patients dose adjustment is not required.
Special notes
At a dose of 4 tablets, the sodium content is 246 mg, which should be considered when you need to follow a diet with a limited salt content (with congestive heart failure, with impaired renal function).
Each dose of 4 pills contains 320 mg of Calcium carbonate. Care must be taken when treating patients with hypercalcemia, nephrocalcinosis and urolithiasis with the formation of oxalate stones.
The drug contains aspartame, so it should not be used in patients with phenylketonuria. Since aspartame is a nonspecific sweetener, patients with diabetes can use the drug Gaviscon®.
Influence on ability to drive motor transport and control mechanisms
The drug does not affect the ability to drive vehicles and mechanisms, as well as the occupation of other potentially hazardous activities,requiring increased concentration and speed of psychomotor reactions.
Overdosage
Symptoms: bloating.
Treatment:conducting symptomatic therapy.
Drug interaction
The composition of the drug includes calcium carbonate, which shows antacid activity, therefore, between taking the drug Gaviscon® and other drugs should take at least 2 hours, especially when used simultaneously with histamine H blockers.2-receptors, antibiotics from the Tetracycline group, Digoxin, fluoroquinolones, iron salts, Ketoconazole, neuroleptics, levothyroxine sodium, thyroid hormones, penicillamine, beta-adrenergic blockers (atenolol, Metoprolol, propranolol), OCo, OCo, OCo, OCo, OCo, OCo, OCo, OCo, OCo, OCo, OCo, OCo, OCEN, OCOM, OCOM, OCOM, OCOM, OCH, OX, OXC
Terms and conditions of storage
The drug should be stored out of the reach of children at a temperature not higher than 30 ° C. Shelf life - 2 years.