Zyprexa pills coated 10mg №28

Zyprexa /Zyprexa

Composition and release form

Zyprexa-tablets:

1 coated pill contains olanzapine 5; 7.5 or 10 mg; 28 pieces per pack.

pharmachologic effect

Zyprexa has an antipsychotic effect. Being a ligand of serotonin (2A / 2C, 3, 6), dopamine (D1-D5), m-cholino (m1-m5), histamine H1 and alpha1-adrenoreceptors, it selectively affects the limbic system.

Indications

Acute form of schizophrenia and other psychoses, accompanied by pronounced positive (delusions, hallucinations, mental disorders, hostility, suspicion) and / or negative (dull affect, emotional and social isolation, poverty of speech activity) symptoms. Secondary affective symptoms on the background of schizophrenia and comorbid disorders.

Contraindications

Hypersensitivity.

Use during pregnancy and lactation

If necessary, the appointment during pregnancy should carefully correlate the expected benefits to the mother and the risk to the fetus. During lactation, breastfeeding should be stopped by nursing mothers.

Side effects

Frequent (more than 10%) - drowsiness, weight gain; rare (less than 10%) - dizziness, dry mouth, constipation, peripheral edema, orthostatic hypotension, akathisia, dystonias, eosinophilia (asymptomatic), a small and temporary increase in the level of prolactin (gynecomastia, lactorrhea),hepatic transaminase activity.

Dosage and administration

Zyprexu is taken orally, regardless of the meal. The initial dose of 10 mg / day, once. Then the daily dose may vary from 5 to 20 mg / day, depending on the clinical condition.

special instructions

Zyprexa is prescribed with caution in patients with prostate hypertrophy, angle-closure glaucoma, paralytic intestinal obstruction, the presence of convulsive conditions in history, liver and kidney diseases; in patients with altered hematological parameters; as well as in combination with other means of depressing the central nervous system (including with alcohol). It is not recommended to manage potentially dangerous mechanisms (vehicles, etc.) during treatment.

Storage conditions and shelf life

The drug should be stored in a dry, dark place at temperatures not above 20 ° C. Shelf life - 3 years.