Pantocalcin pills 250mg №50

Composition

Pantocalcin pills - white, flat-cylindrical shape, with a facet and risky.
1 pill contains: Pantogam or Calcium hopantenate - 250 mg or 500 mg;
Excipients: Magnesium carbonate basic, calcium stearate, talc, potato starch;
5 pills per pack.

Pharmacology

- nootropic agent.
The spectrum of action is associated with the presence in the structure of gamma-aminobutyric acid. The mechanism of action is due to the direct effect of pantocalcine on the GABCR - receptor-channel complex. It has neurometabolic, neuroprotective and neurotrophic properties. Increases the brain's resistance to hypoxia and the effects of toxic substances, stimulates anabolic processes in neurons. It has anticonvulsant action, reduces motor excitability with simultaneous streamlining of behavior. Enhances mental and physical performance. It contributes to the normalization of gamma-aminobutyric acid in chronic alcohol intoxication and the subsequent abolition of ethanol. Shows analgesic effect. Able to inhibit acetylation reactions involved in the inactivation mechanisms of Novocaine and sulfonamides, which results in a prolonged action of the latter.It causes inhibition of the pathologically increased gallbladder reflex and detrusor tone.

Indications and usage

• cognitive impairment in organic brain lesions and neurotic disorders;
• in the complex therapy of cerebrovascular insufficiency caused by atherosclerotic changes in the cerebral vessels; senile dementia (initial form), residual organic brain damage in people of mature age and the elderly;
• cerebral organic insufficiency in patients with schizophrenia (in combination with antipsychotics, antidepressants);
• extrapyramidal hyperkinesis in patients with hereditary diseases of the nervous system (Huntington's chorea, hepatocerebral dystrophy, Parkinson's disease, etc.);
• consequences of neuroinfection and craniocerebral injuries (as part of complex therapy);
• for the correction of side effects of neuroleptics and prophylactically at the same time as “cover therapy”; extrapyramidal neuroleptic syndrome (hyperkinetic and akinetic);
• epilepsy with a slowdown in mental processes (in combination with anticonvulsants);
• psycho-emotional overload, reduced mental and physical performance, to improve concentration and memorization;
• urinary disorders: enuresis, daytime incontinence, pollakiuria, imperative urges (adults and children from 3 years);
• children with perinatal encephalopathy, mental retardation (mental retardation, speech, motor development, or a combination thereof); cerebral palsy; stuttering (predominantly clonic form), epilepsy (as part of combination therapy with anticonvulsant drugs, especially during polymorphic seizures and minor epileptic seizures).

Contraindications

Hypersensitivity; acute renal failure; pregnancy (1 trimester). Children's age of three years for this dosage form)

Dosage and administration

take orally 15-30 minutes after meals.
Single dose for adults makes 0,5-1 g, for kids - 0.25-0.5 g. Daily dose for adults - 1.5-3 g, for children - 0.75-3 g.
The duration of treatment is from 1 to 4 months, in some cases up to 6 months. After 3-6 months, it is possible to repeat the course of treatment.

For children with mental deficiency: 0.5 g 4-6 times a day, daily for 3 months, with delayed speech development - 0.5 g 3-4 times a day for 2-3 months.
In neuroleptic syndrome (as a corrector side effects of antipsychotic drugs): adults, 0.5-1 g, 3 times a day, children - 0.25-0.5 g, 3-4 times a day. Duration of treatment is 1-3 months.
With epilepsy: children 0.25-0.5 g 3-4 times a day, adults 0.5-1 g 3-4 times a day every day for a long time (up to 6 months).
When hyperkinesis (tick): children 0.25-0.5 g 3-6 times a day, daily for 1-4 months, adults, 1.5-3 g daily, for 1-5 months.
For urination disorders: Adults take 0.5-1 g 2-3 times a day (daily dose 2-3 g), children - 0.25-0.5 g (daily dose 25-50 mg / kg). The duration of treatment is from 2 weeks to 3 months (depending on the severity of the disorder and the therapeutic effect).
With the consequences of neuroinfections and traumatic brain injuries of 0.25 g 3-4 times a day
To restore performance at elevated loads and asthenic conditions of 0.25 g 3 times a day.

Adverse reactions

Allergic reactions are possible: rhinitis, conjunctivitis, skin rashes.

Drug interactions

Pantocalcin prolongs the action of barbiturates; enhances the effects of drugs that stimulate the central nervous system, anticonvulsant drugs, the action of local anesthetics (procaine). It prevents the side effects of phenobarbital, Carbamazepine, antipsychotics (neuroleptics).
The effect of hopantenic acid is enhanced in combination with Glycine, ksifiponom.

Storage conditions

Store in a dry, protected from light, out of reach of children, at a temperature not exceeding 25 ° C.
Shelf life - 3 years.