Vikasol ampoules 1% 1 ml №10

Mechanism of action

Vikasol is a synthetic water-soluble analogue of vitamin K, promotes the synthesis of prothrombin and proconvertin, increases blood clotting by enhancing the synthesis of II, VII, IX, X hemocoagulation factors. It has a hemostatic effect (with a deficiency of vitamin K, increased bleeding occurs). The effect appears 12-18 hours after intramuscular administration.

Indications and usage

Hemorrhagic syndrome associated with hypoprothrombinemia; hypovitaminosis K (including obstructive jaundice, hepatitis, liver cirrhosis, prolonged diarrhea), bleeding after injuries, injuries and surgical interventions, as part of complex therapy of dysfunctional uterine bleeding, menorrhagia. Treatment and prevention of hemorrhagic disease of the newborn. An overdose of drugs - antagonists of vitamin K (neodikumarina, fenilina, etc.).

Contraindications

Hypersensitivity to the drug. Increased blood clotting, thromboembolism. Hemolytic disease of the newborn.

Carefully: deficiency of 6-phosphate dehydrogenase, liver failure, pregnancy.

Dosage and administration

Adults Vikasol prescribed inside 15-30 mg per day; intramuscularly - 10 -30 mg per day.
Children under the age of 1 year - 2-5 mg per day, from 1 to 2 years old - 6 mg per day, 3-4 years - 8 mg per day, 5-9 years - 10 mg per day, 10- 14 years - 15 mg per day. Reception frequency - 2-3 times a day.
The maximum daily dose of the drug for newborns - 4 mg.
Duration of treatment is 3-4 days. The course of treatment is repeated after 4 days break.

Drug Interactions

Reduces or blocks the anticoagulant action of neodicoumarin and fenilina. Does not affect the anticoagulant activity of Heparin. Simultaneous administration with broad-spectrum antibiotics, quinidine, quinine, high-dose salicylates, antibacterial sulfonamides requires an increase in the dose of vitamin K.

Special notes

In hemophilia, von Willebrand and Verlgof disease, the drug is ineffective. If glucose-6-phosphate dehydrogenase is deficient, it can cause hemolysis.

Storage conditions

In the dark place.