Pimafucin candles vaginal 100mg №6

Drug description

Packaging

In the blister 3 suppositories. In packing 2 blisters.

Mechanism of action

Pimafucin is an antifungal polyene macrolide antibiotic with a wide spectrum of action. It has a fungicidal effect. Natamycin binds sterols of cell membranes, violating their integrity and function, which leads to the death of microorganisms. The majority of pathogenic yeasts are sensitive to natamycin, especially Candida albicans. Dermatophytes are less sensitive to natamycin. Natamycin resistance is not found in clinical practice.

Indications and usage

Vaginitis, vulvitis, vulvovaginitis, balanoposthitis, caused mainly by Candida fungi.

Contraindications

Hypersensitivity to the drug.

Pregnancy and Breastfeeding

Perhaps the use of Pimafucin during pregnancy and lactation.

Dosage and administration

In case of vaginitis, vulvitis, vulvovaginitis, 1 vaginal suppository is prescribed for 3-6 days.The suppository is inserted into the vagina in the prone position, as deep as possible, 1 time / day for the night. In case of persistent course of vaginitis caused by Candida albicans, an additional oral preparation is prescribed (Pimafucin tablets.d. diss. / Intestinal. 100 mg pack. 20 Yamanouchi Europe BV, 1 tab. 4 times a day for 10-20 days) for the rehabilitation of the focus of candidal infection in the intestine.

The duration of treatment is set individually. After the disappearance of the symptoms of the disease, it is recommended to continue the treatment for a few more days.

Adverse reactions

Local reactions: slight irritation, burning sensation.

Vaginal suppositories under the action of body temperature quickly dissolve, forming a foamy mass, which contributes to the uniform distribution of the active substance. Cetyl alcohol, which is part of vaginal suppositories, can cause hypersensitivity reactions. During menstruation, suppository therapy is interrupted.

During the period of use of suppositories there is no need to exclude sexual contacts. However, it is recommended to conduct a survey of sexual partners and, in the event of a candidal lesion, conduct a course of treatment with Pimafucine. Also during the period of treatment should use barrier contraceptives.

Storage conditions

Store at a temperature not exceeding 25 ° C.

2 years.